基于常规体检人群高尿酸血症患病率调查.docVIP

基于常规体检人群高尿酸血症患病率调查 　　摘要：目的 了解四川省遂宁市常规体检人群高尿酸血症的患病率现况。方法 采用典型抽样的方法选择2014年1月～2015年10月在四川省遂宁市中医医院进行常规健康体检的人群作为研究对象，收集全部研究对象的体检资料，分析血尿酸及血脂六项水平。结果 2301例体检对象的血尿酸平均水平为（289.27±65.24） μmol/L，体检人群高尿酸血症的总体患病率为16.38%（377/2301）；其中，男性患病率24.23%（299/1234）、女性患病率7.31%（78/1067），体检人群中男性的患病率明显高于女性（24.23% VS. 7.31%；χ2=119.577， P0.001 ）。性别分层后，男性、女性HUA患者的TG、TC、LDL-C水平均高于尿酸正常人群，而HUA患者的HDL-C水平则低于尿酸正常者，差异均有统计学意义（P0.05）。结论 四川省遂宁地区HUA患病率较高，存在明显的性别差异；同时发现尿酸水平与血脂代谢关系密切。 　　关键词：体检人群；高尿酸血症；患病率；调查 　　Prevalence of Hyperuricemia in a Population of Routine Check-up 　　HE Jun，WANG Xing-shuan，ZHANG Ya-chun 　　（Department of Endocrinology，Suining Municipal Hospital of TCM， Suining 629000，Sichuan，China） 　　Abstract：Objective To investigate the prevalence of hyperuricemia in a population of routine check-up. Methods The typical sampling method was adopted to select the physical examination data of population of routine check-up in Suining Municipal Hospital of TCM from January 2014 to October 2015， and to collect all the physical examination data， and to analyze the six levels of blood lipid and serum uric acid. Results 2301 cases of blood uric acid level study was （289.27±65.24） μmol / L， high blood uric acid disease medical groups overall prevalence of 16.38% （377/2301）； wherein the male prevalence rate 24.23% （299/1234 ）， female prevalence rate 7.31% （78/1067）， physical examination population prevalence of male than female （24.23% VS. 7.31%； χ2=119.577， P0.001）. After gender stratification， male， female HUA patients TG， TC， LDL-C levels were higher than normal uric acid group， and HDL-C levels in patients with HUA lower than normal uric acid， the differences were statistically significant （P0.05）. Conclusion HUA prevalence is higher in Suining area， there are significant gender differences； also found that uric acid and lipid metabolism are closely related. 　　Key words：Physical examination population； Hyperuricemia； Prevalence；Survey 　　尿酸是人类嘌呤化合物代谢的终末产物，嘌呤代谢紊乱会导致高尿酸血症。高尿酸血症（hyperuricemia， HUA）是指在正常嘌