纳米乳的研究进展与其在药剂学与食品工业中应用.docVIP

纳米乳的研究进展及其在药剂学及食品工业中应用 摘要：纳米乳是由水相、油相、表面活性剂和助表面活性剂按适当比例形成粒径为10 ～100 nm，具低黏度、各向同性的热力学和动力学稳定的透明的或半透明体系。粒径100 ～ 1000 nm 的为亚微乳。有人将二者统称为微乳。本文综述了纳米乳的各组分组成、制备工艺、及在药剂学领域和食品工业领域中的应用。 关键词: 纳米乳；制备工艺；稳定性；应用；药剂学；食品工业 Progress in applications of nanocarriers and apply in Pharmaceutics and Food industry [Abstract] Nanoemulsion is organized with the oil phase, surfactant and co-surfactant which is formed by an appropriate proportion of water, particle size 10 ~ 100 nm, with a low viscosity, isotropic and thermodynamically or kinetically stable and transparent Translucent system. Particle size of 100 ~ 1000 nm is submicroemulsion. From the particle size of the watch, the nanoemulsion is a transitional thing micelles and emulsion between both micelles and emulsion properties, they have the essential difference; From a structural perspective, the nanoemulsion can be divided into oil-in-water (O / W), water-in-oil (W / O) and bi-continuous type. Nanoemulsion preparation is simple, safe, thermodynamically stable, can increase the solubility of poorly soluble drugs, and improve the stability of the drug easily hydrolyzed,.Its slow release, targeting can improve the bioavailability of the drug. Cyclosporine.Preparation, evaluation system, stability and in the field of pharmacy applications and micro-emulsion technology in the food industry and its progress in the text summarizes the nanoemulsion. Pointed out that the use of micro-emulsion technology to study the solubilization of nutrients in the food is a very promising development, increase in food applications of micro-emulsion technology for the development of the food industry will play an important role. [Keywords] nanoemulsion; preparation process; stability; application; Pharmaceutics; food industry 纳米乳( nanoemulsion) 是由水相、油相、表面活性剂和助表面活性剂按适当比例形成粒径为10 ～100 nm，具低黏度、各向同性的热力学和动力学稳定的透明的或半透明体系。粒径100 ～ 1000 nm 的为亚微乳。有人将二者统称为微乳( microemulsion)。从质点大小看，纳米乳是胶团和乳状液之间的过渡物，兼有胶团和乳状液的性质，又有着本质差异; 从结构看，纳米乳可分为水包油型( O/W) 、油包水型( W/O) 及双连续型[3]。纳米乳制备简单、