少年男子中长跑运动员10 km训练跑对血清心肌损伤标志物水平影响.docVIP

少年男子中长跑运动员10 km训练跑对血清心肌损伤标志物水平影响 　　摘 要： 目的：观察常规训练中非力竭耐力运动前后少年运动员血清心肌损伤标志物水平的变化。方 法：测定19名少年男子中长跑运动员在常规训练中一次非全力10 km跑前、运动后2 h、运动 后4 h以及运动后24 h血清心肌肌钙蛋白T亚基(cTnT)、I亚基(cTnI)、CK-MB 活性及CK-MB质量水平。结果：10 km跑可显著提高被试者血清cTnT、cTnI及CK-MB质量水平 。运动后4 h内血清cTnT和cTnI可超过临床心肌损伤(60%以上被试者)甚至心肌梗死(10.5% ～ 42.1%被试者)界值，而运动后24 h，血清cTnT及cTnI恢复至正常水平。另外，运动前后各 观察点都有相当比例的被试者（15.8%～84.2%）CK-MB活性及质量超过心肌损伤界值。结 论： 非力竭性耐力运动可能引起少年运动员可逆性心肌微损伤，但其确切机制、临床意义及远期 后果有待进一步研究。 　　关键词：心肌标志物；耐力运动；心肌损伤；少年运动员 　　中图分类号：G804.2文献标识码：A文章编 号：1007-3612(2011)03-0052-04 　　 　　Effects of 10 km Run on Serum Cardiac Markers in Junior Male Ru nners Training 　　SHI Qing de1，NIE Jin lei1，LIU Wei2 　　(1.School of Physical Education and Sports， Macao PolytechnicInstitute，Macao 999078， China； 　　2. Department of Cardiology， Beijin g Hospital， Ministry of Health，Beijing 100730，China) 　　Abstract: Purpose: This study was designed to examine the appearance and clearance charact eristics of serum cardiac markers in junior runners after a non exhaustive endu rance exercise.Method:19 trained male adolescents performed non all out 10km run during routine training.The levels of cTnT，cTnI and CK MB mass，an d activities of CK MB immediately before and two，four and twenty four hoursafter exercise were measured.Results: At pre exercise，cTnT and cTnI were atthe normal range. However，CK MB activity and CK MB mass were above corresp onding clinical cut off values for myocardial injury.Post exercise significa nt elevations above pre exercise were observed for all biomarkers， except CKMB activity，two and four hours following the run.Similar changes were observ ed in the biomarkers positive rate in the subjects.Conclusions: Such findingssuggest that non exhaustive long distance run during routine training might l ead to reversible minor myocardial injury in junior runners. However， its clin ical significance， long term consequences and mechanism remain to be fully elu cidated. 　　Key words: cardiac markers； endurance exercise； myocardial damage； ju nio