急诊内科中抗生素临床合理应用及耐药分析.docVIP

急诊内科中抗生素临床合理应用及耐药分析 　　[摘要] 目的 分析急诊内科中抗生素的合理应用及耐药情况。 方法 选择2012年1月～2013年4月本院急诊内科开具的2015张抗生素应用处方为研究对象，分析抗生素合理用药情况，并随机选取其中500例抗生素应用患者进行药敏试验及细菌培养，观察抗生素的耐药性情况。 结果 实际应用中2种抗生素联用者占50.22%，明显高于1种抗生素、3种及以上抗生素联用的比例，差异有统计学意义（P0.05）；头孢类抗生素应用比例（占72.70%）明显高于其他种类抗生素（P0.05）；119例存在不合理用药现象，占5.91%，主要为药物配伍不合理、给药方式不合理、溶媒不对等。 结论 临床中抗生素有严格的应用原则，但临床依然存在诸多用药不合理现象，应用时还需考虑其耐药性，合理选择药物种类。 　　[关键词] 急诊内科；抗生素；临床合理应用 　　[中图分类号] R969.3 [文献标识码] A [文章编号] 1674-4721（2013）11（b）-0163-02 　　Clinical reasonable application and resistance analysis of antibiotics in emergency medicine 　　HOU Yun QIN Cheng-du 　　Department of Emergency，Liuzhou Iron and Steel Group Corporation Workers Hospital of Guangxi Zhuang Autonomous Region，Liuzhou 545002，China 　　[Abstract] Objective To investigate the clinical reasonable application and resistance analysis of antibiotics in emergency medicine. Methods 2015 emergency medicine issued prescriptions of antibiotics in our hospital from January 2012 to April 2013 were selected as the research object.Clinical reasonable application and resistance of antibiotics was analyzed.500 cases of patients with antibiotic were took susceptibility testing and bacterial culture and antibiotic resistance was summarized. Results In practical application，combined with two kinds of antibiotics accounted for 50.22%，which was significantly higher than one antibiotic and above three kinds of antibiotics combined application （P0.05）；the cephalosporin antibiotics（accounted for 72.70%） was significantly higher than the other types antibiotics（P0.05）；119 cases of patients existed irrational drug phenomenon（accounted for 5.91%），mainly for drug compatibility unreasonable，irrational mode of administration，solvents unequal. Conclusion Clinical application principles of antibiotics are strict，but there are still many clinical medicine anomaly applications，we need to consider the drug resistance and a reasonable choice types of drugs. 　　[Key words] Emergency medicine；Antibiotics；Clinical reasonable applicat