微波消融联合肝动脉插管化疗栓塞术与手术切除巴塞罗那B期原发性肝癌临床疗效分析.docVIP

微波消融联合肝动脉插管化疗栓塞术与手术切除巴塞罗那B期原发性肝癌临床疗效分析 　　[摘要]目的 比较微波消融联合经导管化疗栓塞术（TACE）和手术切除治疗巴塞罗那分期B期（BCLC-B）原发性肝癌患者的生存及预后。方法 回顾性随机收集2010年1月～2013年6月河南中医学院第一附属医院的40例BCLC-B期原发性肝癌患者，按初治方式的不同将患者分为微创组及手术组，各20例，微创组采用微波消融联合TACE，手术组采用手术切除，比较两组患者的近远期治疗效果。结果 微创组及手术组平均随访3年生存率分别为85%及55%，差异有统计学意义（P=0.04）。结论 微波消融联合TACE术对BCLC-B期原发性肝癌疗效肯定，临床可考虑将其作为BCLC-B期原发性肝癌的首选治疗手段。 　　[关键词]原发性肝癌；微波消融；经导管化疗栓塞术；手术切除 　　[中图分类号] R735.7 [文献标识码] A [文章编号] 1674-4721（2016）12（a）-0069-03 　　Clinical efficacy analysis of microwave ablation combined with transcatheter arterial chemoembolization and surgical resection for patients with primary hepatocellular carcinoma of BCLC-B 　　WANG Xin-ting ZHANG Chuan-lei CHEN Xiao-qi CHEN Xin-ju 　　Department of Gastroenterology，the First Affiliated Hospital of Henan University of Traditional Chinese Medicine in Henan Province，Zhengzhou 450000，China 　　[Abstract]Objective To compare survival and prognosis of microwave ablation combined with transcatheter arterial chemoembolization （TACE） and surgical resection for patients with primary hepatocellular carcinoma of BCLC-B.Methods Clinacal date of 40 patiens who were diagnosed as primary hepatocellular carcinoma of BCLC-B in the First Affiliated Hospital of Henan University of Traditional Chinese Medicine from January 2010 to June 2013 were retrospectively analyzed and divided into minimally invasive group and operation group according to the different treatment methods，each group of 20 cases，patients in the minimally invasive group was treated with microwave ablation combined with TACE，while patients in the operation group was treated by surgical resection，near and long-term treatment effect in two groups were compared.Results The 3-year survial rates were 85% in the minimally invasive group，and 55% in the operation group，and the difference was statistically significant （P=0.04）.Conclusion The efficacy of microwave ablation combined with TACE in the treatment of primary hepatocellular carcinoma of BCLC-B is affirmat，and it could be con