无创正压通气治疗慢阻肺急性加重期呼吸衰竭临床疗效观察.docVIP

无创正压通气治疗慢阻肺急性加重期呼吸衰竭临床疗效观察 　　[摘要] 目的 探讨无创正压通气治疗COPD合并呼吸衰竭的疗效。 方法 选择 76例符合入选标准的患者随机分为两组，对照组给予传统治疗，实验组在传统治疗的基础上应用无创正压通气治疗，比较两组疗效。 结果 两组治疗后72 h，临床症状及血气指标改善比较差异有统计学意义（P0.05）。实验组有效36例，无效2例，有效率为94.74%；对照组有效25例，无效13例，有效率为65.79%；两组疗效比较，差异有统计学意义（P0.05）。 结论 无创正压机械通气结合传统疗法治疗COPD合并呼吸衰竭具有较好的疗效。 　　[关键词] 无创正压机械通气；慢阻肺；呼吸衰竭 　　[中图分类号] R563.9 [文献标识码] B [文章编号] 1673-9701（2015）22-0083-03 　　Observation of clinical efficacy of noninvasive positive pressure ventilation on respiratory failure associated with acute exacerbation of COPD 　　LI Xiaoshu 　　Department of Emergency Medicine， Mentougou District Hospital of Beijing City， Beijing 102300， China 　　[Abstract] Objective To explore the efficacy of noninvasive positive pressure ventilation in the treatment of COPD associated with respiratory failure. Methods Seventy-six patients meeting the inclusion standards were randomly divided into two groups. The control group was given traditional treatment and the experimental group was given noninvasive positive pressure ventilation treatment on the basis of traditional treatment. The efficacy of the two groups was compared. Results Seventy-two hours after treatment， the clinical symptoms and blood gas indicators of both groups improved， with statistically significant difference between the two groups（P0.05）. In the experimental group， 36 patients were effective and 2 patients were ineffective， with the effective rate of 94.74%. In the control group， 25 patients were effective and 13 patients were ineffective， with the effective rate of 65.79%. In terms of efficacy， the two groups were statistically different（P0.05）. Conclusion Noninvasive positive pressure ventilation combined with traditional treatment shows good efficacy in the treatment of COPD associated with respiratory failure. 　　[Key words] Noninvasive positive pressure ventilation； COPD； Respiratory failure 　　慢阻肺即慢性阻塞性肺疾病（COPD）是一种常见的呼吸系统慢性疾病，是导致呼吸衰竭的最常见病因[1]。临床上传统的治疗方法是抗感染、祛痰、平喘、氧疗等综合治疗，对于重症患者需要机械通气。其分为有创通气与无创通气。有创通气需要进行气管插管或气管切开，其