乳腺弥散加权成像原理和临床应用.pptVIP

Normal Breast Parenchyma In contrast, owing to the lower ADC value of normal breast parenchyma at this time, the difference in signal contrast and ADC value between the normal breast and breast tumor may be smaller in week 2 of the cycle; therefore, diffusion-weighted imaging of the breast may not be appropriate in week 2. Figure 6 shows changes in signal intensity and ADC value during the menstrual cycle. 与此相反，由于正常乳腺组织在这个时期ADC值较低，所以在月经周期的第二周，正常乳腺和乳腺肿瘤之间信号对比和ADC值的不同将减小；因此，在第二周施行乳腺弥散加权成像也许并不合适。图8显示了在月经周期期间信号强度和ADC值的变化。 Figure 6. Changes in signal intensity and ADC value during the menstrual cycle in a 27-year-old woman. A focal asymmetric density was seen at mammography. 一个27岁女性月经周期期间信号强度和ADC值的变化。乳腺钼靶上可见局灶性不对称密度影 (a) Contrast-enhanced T1-weighted MR image obtained on day 22 of the menstrual cycle shows nonspecific punctate enhancement in both breasts. 月经周期第22天，对比增强T1加权磁共振成像上显示两侧乳房非特异性点状增强。 (b) On a diffusion-weighted image obtained at b = 1500 sec/mm2 at the same time as a, no high-signal-intensity lesion is observed. 在与a同一个周期的b值等于1500 sec/mm2弥散加权图像上，未发现高信号强度的病灶 (c) Contrast-enhanced T1-weighted MR image obtained on day 2 of the menstrual cycle shows diffuse contrast enhancement in both breasts. 月经周期的第二天，对比增强T1加权磁共振成像显示双侧乳腺弥漫性对比增强 (d) On a diffusion-weighted image (b = 1500 sec/mm2) obtained at the same time as c, slight diffuse nodular high signal intensity is observed in both breasts. The ADC value of breast tissue is higher on day 2 (2.26 × 10-3 mm2/sec) than on day 22 (1.87 × 10-3 mm2/sec). 在与c同一个周期的b值等于1500 sec/mm2弥散加权图像上，双侧乳腺可见轻微的弥漫性结节状高信号强度。乳腺组织的ADC值在月经周期的第二天(2.26 × 10-3 mm2/sec)高于月经周期的第22天(1.87 × 10-3 mm2/sec) * Diffusion-weighted Imaging of the Breast: Principles and Clinical Applications 何杰 2013年12月25日 乳腺弥散加权成像：原理和临床应用 Diffusion-weighted imaging is a modality that makes use of magnetic resonance (MR) imaging to depict the diffusivity of water molecules in a defined voxel by means of the application of motion-probing gradients. This imaging prope