母牛分枝杆菌对复治涂阳肺结核患者防治实践评价.docVIP

母牛分枝杆菌对复治涂阳肺结核患者防治实践评价 　　[摘要] 目的 探?母牛分枝杆菌对复治涂阳肺结核患者的防治效果。 方法 选取我院在2013年3月～2015年4月收治的86例复治涂阳肺结核患者作为本次研究的对象，将其按入院时间分为观察组与对照组，每组43例。两组患者均给予常规治疗方案，观察组患者在此基础上加用母牛分枝杆菌进行治疗。对比两组患者治疗之后的X线变化、空洞闭合情况、治疗后各个时间段的痰菌转阴率、复发率。 结果 观察组患者的X线病灶明显吸收率为76.74%，空洞闭合率为72.09%；对照组患者的X线病灶明显吸收率为32.56%，空洞闭合率为34.88%；组间比较差异有统计学意义（P0.05）。观察组患者在治疗后各个时间段的痰菌转阴率与对照组相比，差异有统计学意义（P0.05）。对两组患者进行为期一年的随访，发现观察组复治涂阳肺结核的复发率为0.00%，对照组为11.63%，组间比较差异有统计学意义（P0.05）。 结论 复治涂阳肺结核患者使用母牛分枝杆菌进行治疗，能够全面提高治疗的总有效率，促进患者的预后，使患者早日恢复正常生活，且母牛分枝杆菌具有一定的预防作用，能够阻止复治涂阳肺结核的再次复发，值得临床推广应用。 　　[关键词] 复治涂阳肺结核；母牛分枝杆菌；预防；痰菌转阴率；复发率 　　[中图分类号] R520.5 [文献标识码] B [文章编号] 1673-9701（2017）15-0084-04 　　[Abstract] Objective To study the effect of cow mycobacterium on the prevention and treatment of retreated smear-positive pulmonary tuberculosis patients. Methods A total of 86 patients with retreated smear-positive pulmonary tuberculosis who were treated in our hospital from March 2013 to April 2015 were enrolled in this study. The patients were divided into observation group and control group according to the time of admission， with 43 patients in each group. The two groups of patients were treated with conventional treatment program， and the observation group of patients was also given cow mycobacterium on this basis. The X-ray changes， cavity closure case after treatment， and the sputum negative rate， recurrence rate in each time period after treatment between the two groups were compared. Results The obvious absorption rate of X-ray lesion was 76.74% and the cavity closure rate was 72.09% in the observation group. The obvious absorption rate of X-ray lesion was 32.56% and the cavity closure rate was 34.88% in the control group. The difference was statistically significant（P 　　[Key words] Retreated smear-positive pulmonary tuberculosis； Cow mycobacterium； Prevention； Sputum negative rate； Recurrence rate 　　肺结核属于临床上的常见病，具有病程长、易反复发作、治疗难度大、传染性强等特点，主要临床症状为咳嗽、胸痛、咳痰、咯血、发热等，对患者的生活质量以及生命安全均有着较大的威胁[1]。涂阳肺结核是指患者的痰涂片检查呈阳性的一种肺结核，此种检验方法具有快速、准确等特点，因此被广泛应用于临床[2]。目