糖尿病66例经胰岛素联合二甲双胍治疗疗效分析.docVIP

糖尿病66例经胰岛素联合二甲双胍治疗疗效分析 　　[摘要] 目的 分析糖尿病患者采用二甲双胍与胰岛素联合进行治疗的临床效果。方法 方便选择在2014年12月―2016年12月该院收治的患有糖尿病的患者132例，将其随机分为对照组和治疗组，平均每组66例。对照组采用门冬胰岛素进行治疗；治疗组采用甘精胰岛素与二甲双胍联合进行治疗。对比两组用药前后血糖水平改善幅度、糖尿病药物控制总有效率、血糖水平恢复正常时间和糖尿病治疗总时间、药物导致的不良反应例数。结果 治疗组患者用药前后血糖水平改善幅度大于对照组，组间差异有统计学意义（P0.05）；糖尿病药物控制总有效率达到92.4%，高于对照组的74.2%，差异有统计学意义（P0.05）；血糖水平恢复正常时间（8.61±2.47）d和糖尿病治疗总时间（13.37±4.02）d明显短于对照组（12.53±3.08）、（16.48±3.26）d，组间差异有统计学意义（P0.05）；?H有1例药物导致的不良反应出现少于对照组的9例，组间差异有统计学意义（P0.05）。 结论 糖尿病患者采用二甲双胍与胰岛素联合进行治疗，可以在短时间内大幅度改善血糖水平，保证用药安全，提高有效率。 　　[关键词] 糖尿病；二甲双胍；胰岛素；效果 　　[中图分类号] R587.1 [文献标识码] A [文章编号] 1674-0742（2017）05（a）-0158-03 　　[Abstract] Objective To analyze the clinical effect of metformin combined with insulin in the treatment of diabetes mellitus. Methods Convenient selection 132 patients with diabetes in our hospital from December 2014 to in December 2016 were randomly divided into control group and treatment group， with an average of each group of 66 cases. The control group used insulin aspart treatment； treatment group were treated with insulin glargine and metformin treatment. Comparison of the two groups before and after treatment to improve the level of blood sugar， the total effective rate of diabetes medication， blood glucose levels returned to normal time and the total duration of diabetes treatment， adverse drug reactions caused by the number of cases. Results The treatment group before and after treatment in patients with improved blood glucose levels than in the control group， The difference was statistically significant（P0.05）； diabetes drug control the total effective rate reached 92.4%， higher than 74.2% in the control group， The difference was statistically significant （P0.05）； blood glucose levels returned to normal time（8.61±2.47）d and diabetes total treatment time（13.37±4.02）d was significantly shorter than the control group （12.53±3.08），（16.48±3.26）d， The difference was statistically significant between the groups （P0.05）； only 1 cases of drug induced adverse reactions a