血清尿酸与N末端B型钠尿肽原联合检测在冠心病诊断中价值分析.docVIP

血清尿酸与N末端B型钠尿肽原联合检测在冠心病诊断中价值分析 　　[摘要] 目的 研究分析采用血清尿酸联合N末端B型钠尿肽原（NT-proBNP）检测冠心病的临床诊断价值。方法 选择该院2012年6月―2014年6月收治的120例冠心病患者，作为观察组。按照病情的轻重程度分为稳定性心绞痛组（SAP）40例，不稳定性心绞痛组（UAP）40例以及急性心肌梗死组（AMI）40例。再选择同期在该院接受体检的健康人群40例作为对照组。对比分析两组患者的血清尿酸指数以及治疗前NT-proBNP水平。 结果 观察组患者的血清尿酸检测值和阳性率均显著高于对照组，差异有统计学意义（P0.05）。观察组各组的NT-proBNP水平均显著高于对照组，差异有统计学意义（P0.05）。结论 对于冠心病患者采用血清尿酸联合N末端B型钠尿肽原检测具有重要价值，值得临床广泛运用。 　　[关键词] 血清尿酸；N末端B型钠尿肽原；冠心病 　　[中图分类号] R [文献标识码] A [文章编号] 1674-0742（2015）01（b）-0192-02 　　Analysis of serum uric acid and N terminal B type natriuretic peptide value in diagnosis of coronary heart disease 　　Zhang Liyun Wu Chunbo 　　Dongguan Gaobu Hospital of medical laboratory Guangdong Dongguan City，523270，China 　　[Abstract] Objective analysis of the serum uric acid combined with N terminal B type natriuretic peptide （NT-proBNP） clinical diagnostic value in detecting coronary artery disease. Methods 120 cases of patients with coronary heart disease in our hospital from 2012 June to 2014 June were taken as observation group. According to the severity of the illness is divided into stable angina pectoris （SAP） group 40 patients， unstable angina pectoris （UAP group） and 40 cases of acute myocardial infarction （AMI） in 40 cases. Healthy people choose again underwent physical examination in our hospital 40 cases as the control group. Comparative analysis of two groups of patients with serum uric acid index and NT-proBNP level before treatment. Results the changes of serum uric acid detection groups and positive rate was significantly higher than that in the control group， with significant difference （P0.05）. The observation group of NT-proBNP were significantly higher than those of the control group， with significant difference （P0.05）. Conclusion for patients with coronary artery disease by serum uric acid has important value in combination with N terminal B type natriuretic peptide detection， and has important significance for prognosis evaluation. 　　[Key words] serum uric acid； N terminal B