血清细胞因子及红细胞免疫指标与淋病相关性研究.docVIP

血清细胞因子及红细胞免疫指标与淋病相关性研究 　　【摘要】目的：探讨及分析血清细胞因子及红细胞免疫指标与淋病的关系。方法：选取2011年5月至2014年5月于本院进行诊治的64例淋病患者为观察组，同时期的64名健康人员为对照组，然后将两组人员的血清细胞因子及红细胞免疫指标进行分别统计与比较，并将观察组中不同严重程度及有无并发症者的检测结果进行比较，同时以Logistic分析处理上述指标与淋病的关系。结果：观察组的血清细胞因子明显高于对照组，而红细胞免疫指标均差于对照组，同时较为严重及有并发症的患者检测结果差于其他患者，P均005，有显著性差异，且经Logistic分析处理显示，上述指标均与淋病有密切的关系。结论：淋病患者的血清细胞因子及红细胞免疫指标呈现相对较差的状态，上述血液指标均与淋病有密切的关系。 　　【关键词】血清；细胞因子；红细胞免疫指标；淋病 　　【Abstract】Objectives： To investigate and analyze the relationship between the serum cytokines， erythrocyte immune indexes and gonorrhoea. Methods： 64 patients with gonorrhoea in our hospital from May 2011 to May 2014 were selected as observation group， 64 healthy persons at the same period selected as control group， and the serum cytokines and erythrocyte immune indexes of two groups were respectively analyzed and compared. The detection results of observation group with different severity degree were compared with non-complications group. The relationship between those indexes and gonorrhoea were analyzed by the logistic analysis. Results： The serum cytokines of observation group was obviously higher than that of control group. The erythrocyte immune indexes of observation group were all worse than those of control group. And the detection results of observation group on more serious disease and complications were all worse than those of other patients， all P005， with significant differences. Those indexes all had close relationship to the gonorrhoea by the logistic analysis. Conclusion： The serum cytokines and erythrocyte immune indexes of patients with gonorrhoea is relatively worse and those blood indexes all have close relationship to the gonorrhoea. 　　【Key words】Serum； Cytokines； Erythrocyte immune indexes； Gonorrhoea 　　【中图分类号】R759.2【文献标志码】A 　　淋病为临床并不少见的一类性传播疾病，临床对其重视程度极高，对其的相关研究较多，其中免疫状态的研究并不少见，可有效反映患者发病过程中的机体免疫状态，另外细胞因子也是有效反映机体多方面反应状态的重要指标，因此对其在淋病患者中的变化研究也极为必要，同时分析淋病与上述指标的关系[1，2]，以为疾病的诊治提供依据。本文中我们就血清细胞因子及红细胞免疫指标与淋病的关系进行研究，现将研究结果分析如下。 　　1资料与方法 　　11临床资料 　　选取2011年5月至2014年5月