超声造影对冠心病颈动脉粥样硬化斑块新生微血管评价.docVIP

超声造影对冠心病颈动脉粥样硬化斑块新生微血管评价 　　[摘要] 目的 评价超声造影对冠心病颈动脉粥样硬化斑块新生微血管的临床价值。 方法 选取我院心内科诊断为冠心病的住院患者，收集时间为2012年6月～2014年6月，作为冠心病组，共60例，随机选取来我院进行健康体检的人群60例，定义为对照组。记录患者血常规、尿常规、大便常规、生化指标如空腹血糖、总胆固醇、血甘油三酯、血低密度脂蛋白胆固醇等。常规B超下检查斑块数量，性质（软斑、硬斑），随后再记录造影剂使用后斑块的增强情况。 结果 冠心病组的软斑数量明显多于健康组，分别为（74块、5块），差异有统计学意义（P0.05），本次研究发现通过B超造影下软斑明显增强，增强数量分别为（58块、3块），差异有统计学意义（P0.05）。 结论 冠心病组软斑数量明显多于健康组，硬斑数量少于健康组，软斑内新生微血管明显多于硬斑，新生微血管数量、密度的增高是冠心病的危险因素。 　　[关键词] 超声造影；冠心病；颈动脉粥样硬化；新生微血管 　　[中图分类号] R445.1；R541.4 [文献标识码] B [文章编号] 2095-0616（2015）13-162-03 　　[Abstract] Objective To evaluate the clinical value of contrast-enhanced ultrasound in diagnosis of carotid atherosclerosis plaque neovascularization of patients with coronary heart disease. Methods 60 hospitalized patients who were diagnosed with coronary heart disease in the department of cardiovascular internal medicine of our hospital from June 2012 to June 2014 were selected as coronary heart disease group and 60 people who had physical examination in our hospital were randomly selected as control group. Blood routine， urine routine， stool routine， biochemical indexes including fasting blood glucose，total cholesterol，serum triglyceride，low-density lipoprotein cholesterol etc.of patients were recorded.The number of plaque and characters of plaque（soft plaque， hard plaque）were examined by routine B-ultrasound examination and then enhanced situation of plaque after using contrast agent was recorded. Results The number of soft plaque 74 in the coronary heart disease group was significantly larger than that 5 in the control group，and the difference was statistically significant（P0.05）.It was found in research that soft plaque was significantly enhanced and the increasing number was 58 and 3 respectively.The difference was statistically significant（P0.05）. Conclusion The number of soft plaque in the coronary heart disease group is significantly smaller than that in the control group while the number of hard plaque is larger than that in the control group.The numbe