针灸对体外受精胚胎移植术患者子宫内膜及妊娠结局影响.docVIP

针灸对体外受精胚胎移植术患者子宫内膜及妊娠结局影响 　　【摘要】 目的：分析针灸对体外受精胚胎移植术（IVF-ET）患者子宫内膜及其妊娠结局的临床影响。方法：将本科室接收治疗的68例IVF-ET患者，编号后按照随机数字表法将其分为两组。A组为针药组34例，采用中药加针灸治疗。B组为中药组34例，采用单纯中药方剂治疗。比较两组患者受孕促性腺激素（Gn）用量、用时，胚胎种植成功率、妊娠率等指标。比较两组患者在妊娠期间，绒毛膜促性腺激素（hCG）日子宫内膜形态变化、雌二醇（E2）、孕激素（P）、黄体素（LH）等指标。结果：A组其hCG日的A型内膜比例、获优质胚胎率、胚胎种植成功率、妊娠率指标均明显高于B组（P0.05）。在患者受孕hCG日两组E2、P、LH比较，差异均有统计学意义（P0.05）。A组治疗总有效率为79.41%，显著高于B组的52.94%（P0.05）。两组用药期间未发现过敏现象，未见药物服用过程中消化道刺激症状，均未发生不良反应，且血压、肝肾功能等均无异常或加重者。结论：针灸配合中药疗法?τ谛?IVF-ET患者子宫内膜有明显改善作用，妊娠结局明显优于单纯中药方剂疗法，可以显著提高外受精-胚胎移植的成功率。 　　【关键词】 体外受精-胚胎移植； 针灸； 中药疗法； 妊娠结局 　　Effect of Acupuncture Combined with Chinese Medicine Therapy on Endometrium and Pregnancy Outcome in Patients with IVF-ET/PENG Dong-hua，LIN Hao-chun.//Medical Innovation of China，2017，14（17）：121-125 　　【Abstract】 Objective：To analyze the clinical effect of acupuncture and Chinese Medicine therapy on endometrium and andpregnancy outcome in patients with in vitro fertilization embryo transfer（IVF-ET）.Method：A total of 68 patients with IVF-ET treated in our department were randomly divided into the observation group and the control group by random number method.A group（n=34 cases） was treated with Chinese Medicine therapy combined with acupuncture.B group（n=34 cases） was treated with Chinese Medicine therapy.Gonadotropin（Gn） dosage and administration time，embryo implantation success rate，pregnancy rate and other indicators of two groups were compared.During pregnancy，hCG day endometrial morphological changes，E2，P，LH and other indicators of two groups were compared.Result：A group hCG days of the proportion of type A endometrium，the rate of high quality embryos，embryo implantation success rate，pregnancy rate were significantly higher than those of B group（P0.05）.Pregnancy hCG，E2，P，LH of A group compared with B group，the differences were significant（P0.05）.The total effective rate of A group was 79.41%，which was significantly higher than 52.94% of B group（P0.05）.Conclusion：Acupuncture combined with Chinese Medicine therapy for