非阻断肾动脉腹腔镜肾部分切除术治疗T1a期肾癌临床研究.docVIP

非阻断肾动脉腹腔镜肾部分切除术治疗T1a期肾癌临床研究 　　【摘要】 目的：分析非阻断肾动脉腹腔镜肾部分切除术治疗T1a期肾癌的可行性。方法：回顾性分析2012年2月-2014年5月本院收治的68例T1a期肾癌患者的临床资料，试验组37例实施腹腔镜下非阻断肾动脉肾部分切除术，对照组31例实施腹腔镜下选择性阻断肾动脉肾部分切除术，比较两种术式的手术时间、术中出血量、术中及术后并发症、术后肾功能恢复情况。结果：68例均手术顺利完成，无一例中转开放。两组患者均未输血，试验组与对照组术中出血量分别为（127.6±18.3）、（85.8±9.1）mL，两组比较差异有统计学意义（P0.05）；术后病理报告切缘均为阴性，术中术后无明显并发症。试验组和对照组术后3个月患肾GFR为（36.2±12.4）、（25.9±14.3）mL/min（P0.05）。术后随访12～39个月，患侧肾功能均正常，无肿瘤复发及转移。结论：非阻断肾动脉腹腔镜肾部分切除术治疗T1a期肾癌安全、有效，可最大限度的减少肾热缺血时间，保护患肾功能。 　　【关键词】 腹腔镜肾部分切除术； 肾癌T1a期； 非阻断肾动脉 　　Clinical Analysis of Laparoscopic Partial Nephrectomy for T1a Renal Cell Carcinoma without Clamping Renal Artery/HAO Tong-tong，SUN Jian-tao，YANG Jin-hui，et al.//Medical Innovation of China，2016，13（06）：022-025 　　【Abstract】 Objective： To analyse the feasibility of laparoscopic partial nephrectomy for renal cell carcinoma of T1a stage without clamping of renal artery. Method：The clinical data of 68 patients with T1a renal cell carcinoma who were treated from February 2012 to May 2014 were retrospectively studied.All patients were divided to two groups：the patients of test group （n=37） recieved LPN without clamping of renal artery， and the the patients of control group recieved LPN with clamping of renal artery. Operation time， intraoperative blood loss， intraoperative and postoperative complications， and postoperative recovery of renal function were compared. Result：All the 68 cases were operated successfully， without a case of blood transfusion or transfer to open. The mean blood loss were （127.6±18.3） and （85.8±9.1） mL of the test group and the control group（P0.05）. The GFR were （36.2±12.4） and （25.9±14.3）mL/min of the test group and the control group after 3 months of operation， there was statistically significant difference（P0.05）. There were no complications during and after surgery.Postoperative pathology showed the incisal margin were negative.All patients had normal renal function and had no tumor recurrence or metastasis followed up for 12-39 months. Conclusion：Laparosco