骨痹合剂联合PLIF术治疗退行性腰椎管狭窄症临床观察.docVIP

骨痹合剂联合PLIF术治疗退行性腰椎管狭窄症临床观察 　　摘要：目的探讨应用骨痹合剂联合腰椎后路椎的融合术（PLIF）术治疗退行性腰椎管狭窄症的临床疗效。方法对自2015年1月～2016年1月60例退行性腰椎管狭窄症患者随机分为2组。其中30例给予行PLIF术后服用骨痹合剂，治疗4周（治疗组），30例单纯采用PLIF术治疗（对照组）；采用目测类比评分法（VAS）和腰椎JOA评分系统评估患者治疗前后的评分及改善率状况。结果术后应用骨痹合剂治疗，对 VAS 以及腰椎JOA 评分系统的影响均有显著统计学差异。2组患者根据治疗前和治疗后 4 周 JOA 评分后计算改善率，优 10 例，良18 例，中2例，差0例，平均改善率为72.23%；对照组优 8 例，良19 例，中3例，差0例，平均改善率为58.75%；治疗组改善率明显高于对照组。结论骨痹合剂联合PLIF术治疗退行性腰椎管狭窄症具有良好的临床效果。 　　关键词：腰椎管狭窄；后路椎间融合术；骨痹合剂 　　中图分类号：R274.9文献标志码：B文章编号：1007-2349（2017）01-0048-03 　　【Abstract】Objective：To investigate the clinical effect ofGubi Mixture combined with posterior lumbar interbody fusion（PLIF）on the treatment of degenerative lumbar spinal stenosis patients. Methods：60 PLIF patients from January 2015 to January 2016 were randomly divided into two groups，30 cases per group. One group was treated with PLIF after operation for 4 weeks（treatment group），and another group was treated with PLIF alone（control group）. VAS and JOA scoring system were used to evaluate the score and improvement of the patients before and after treatment. Results：The effect ofGubi Mixture on VAS and JOA scoring system was statistically significant differences. According to the improvement rate of 4-week JOA score in the pre-post treatment，10 cases were excellent，18 good，2 moderate，and 0 poor in the treatment group and the average improvement rate was 72.23%. But 8 cases were excellent，19 good，3 moderate and 0 poor in the control group and the average improvement rate was 58.75%. The improvement rate of the treatment group was significantly higher than that of the control group. Conclusion：Gubi Mixture with PLIF has a good clinical effect on the treatment of degenerative lumbar interbody stenosis. 　　【Key words】lumbar spinal stenosis，posterior lumbar interbody fusion，Gubi Mixture 　　退行性腰椎管?M窄症是一种临床常见严重影响中老年人生活质量的疾病，现代医学大多认为本病是由于腰椎间隙变窄、腰椎小关节增生、黄韧带肥厚、椎体骨质增生等导致腰椎椎管、神经根管、侧隐窝及椎间孔的骨性或软组织性狭窄，进而造成神经、血管受压而发病。PLIF术即腰椎后路椎间融合术（Posterior Lumbar Interbody Fusion），是经后路椎管至椎体间融合的一种术式，是目前治疗腰椎管狭窄症常用的手术方式。