颅内静脉系统血栓形成合并脑出血临床特点与危险因素.docVIP

颅内静脉系统血栓形成合并脑出血临床特点与危险因素 　　[摘要] 目的 探讨颅内静脉系统血栓形成合并脑出血的临床特点，同时分析引发该病的危险因素。方法 方便选取该院2016年1月―2017年1月接诊的颅内经脉系统血栓形成患者88例，根据是否存在脑出血将其分为观察组与对照组，每组44例，观察组患者均合并脑出血，对照组患者未合并脑出血，对比两组患者的一般资料、临床表现、影像学特点、治疗方法以及预后效果进行对比分析。结果 观察组患者合并头痛、意识障碍、运动障碍、痫性发作的比例明显高于对照组（观察组分别为72.70%、20.45%、27.27%、31.81%，对照组分别为59.01%、6.81%、11.36%、15.90%）。根据多因素logistic回归分析发现妊娠、产褥期、多个静脉窦受累与颅内经脉系统血栓形成合并脑出血呈正相关。结论 妊娠和产褥期患者出现颅内静脉系统血栓形成合并脑出血的机率更高，常见的临床表现有头痛、意识障碍、运动障碍、累积多个静脉窦以及痫性发作，预后效果较差。 　　[关键词] 颅内静脉血栓；脑出血；临床特点；危险因素 　　[中图分类号] R743 [文献标识码] A [文章编号] 1674-0742（2017）04（c）-0089-03 　　[Abstract] Objective To summarize the clinical features and risk factors of cerebral venous system thrombosis and cerebral hemorrhage. Methods 88 cases of patients with cerebral venous system thrombosis and cerebral hemorrhage treated in our hospital from January 2016 to January 2017 were convenient selected and divided into two groups with 44 cases in each， the observation group were with cerebral hemorrhage， while the control group were without cerebral hemorrhage， and the general data， clinical performance， imaging features， treatment method and prognosis effect were compared between the two groups. Results The ratio of patients with headache， disturbance of consciousness， dyskinesia and epileptic seizure in the observation group was obviously higher than that in the control group（72.70%，20.45%，27.27%，31.81% vs 59.01%，6.81%，11.36%，15.90%）， and the multiple-factor logistic regression analysis showed that the pregnancy， puerperium and sinus venosus invovemnet were positively correlated with cerebral venous system thrombosis and cerebral hemorrhage. Conclusion The occurrence probability of cerebral venous system thrombosis and cerebral hemorrhage is higher of patients with pregnancy and puerperium， and the common clinical manifestations are headache， disturbance of consciousness， dyskinesia and epileptic attack， and the prognosis effect is bad. 　　[Key words] Cerebral venous system thrombosis； Cerebral hemorrhage； Clinical features； Ris