高血压脑出血患者治疗中依达拉奉对脑血管血液动力学参数及神经功能影响分析.docVIP

高血压脑出血患者治疗中依达拉奉对脑血管血液动力学参数及神经功能影响分析 　　【摘要】 目的：分析高血?耗猿鲅?患者治疗中依达拉奉对脑血管血液动力学参数及神经功能的影响。方法：选取2012年1月-2016年4月203例高血压脑出血患者，将患者分为对照组（n=94）和研究组（n=109）。对照组患者采用常规治疗方法，研究组患者采用依达拉奉治疗，对比两组患者脑血管动力参数脑血管平均流速（Vmean）、脑血管平均流量（Qmean）、血管外周阻力（R）、动态阻力（DR）及临界压（CP），神经功能量表mRS、SSS评分和临床疗效。结果：两组患者治疗前脑血管动力参数Vmean、Qmean、R、DR及CP等比较，差异均无统计学意义（P0.05）。治疗后研究组患者CP、DR和R均低于对照组，Qmean和Vmean均高于对照组，比较差异均有统计学意义（P0.05），两组患者治疗后mRS、SSS评分与各自治疗前对比差异均有统计学意义（P0.05）。研究组患者mRS评分明显低于对照组，SSS评分明显高于对照组，比较差异均有统计学意义（P0.05）。结论：高血压脑出血患者采用依达拉奉治疗可改善患者脑血管功能，改善脑血管动力学参数，神经功能得到提高，提高临床疗效。 　　【关键词】 脑出血； 依达拉奉； 血流动力学； 神经功能 　　【Abstract】 Objective：To analyze the effect of Edaravone on hemodynamic parameters and neurological function in patients with hypertensive intracerebral hemorrhage.Method：A total of 203 patients with hypertensive intracerebral hemorrhage were selected from January 2012 to April 2016 in this study.They were divided into the control group （n=94） and study group （n=109）.The control group was treated with regular treatment.The study group was treated with Edaravone.The cerebrovascular parameters Vmean，Qmean，R，DR and CP，neurological function scale mRS，SSS score and clinical curative effects of two groups were compared.Result：There were no significant differences in Veman，Qmean，R，DR and CP between the two groups before treatment（P0.05）.After treatment，the hemodynamics parameters of CP，DR and R were lower than those in the control group，Qmean and Vmean were higher than those in the control group，the differences were statistical significance（P0.05）. The mRS and SSS scores of the two groups were statistically different from those before treatment（P0.05）.The mRS score of the study group was significantly lower than that of the control group，and the SSS score was significantly higher than that of the control group，the differences were statistically significant（P0.05）.Conclusion：The treatment of Edaravone in patients with hypertensive intracerebral hemorrhage can improve the cerebrovascular function，improve the cerebrovascula