龟龄集胶囊治疗勃起功能障碍疗效观察.docVIP

龟龄集胶囊治疗勃起功能障碍疗效观察 　　【摘 要】 目的:观察龟龄集治疗勃起功能障碍的疗效。方法:采用多中心、安慰剂对照试验的临床研究方法,180例患者随机分为试验组和对照组,试验组患者采用口服龟龄集胶囊治疗,对照组采用安慰剂治疗,疗程为4周,以IIEF-5为主要疗效指标,以患者伴随症状为次要疗效指标,来评价龟龄集胶囊治疗效果。结果:有164例患者完成了临床研究,试验组88例患者,显效36例,有效24例,无效28例,总有效率68.2%;对照组86例患者,显效20例,有效13例,无效53例,总有效率38.4%,两组疗效比较差异显著有统计学意义(P0.01)。试验组治疗前IIEF-5评分为 12.6±2.3,治疗后为21.8±2.6;对照组治疗前IIEF-5评分为11.5±3.1,治疗后为14.8±4.4,两组疗效比较差异显著有统计学意义(P0.01)。试验组能改善患者IIEF-5评分情况;试验组患者治疗后腰膝酸冷、疲乏无力、性欲淡漠、精神萎靡、畏寒肢凉等症状较治疗前明显好转。结论:龟龄集对勃起功能障碍患者有显著疗效,可改善其伴随症状,且未见明显不良反应。 　　【关键词】 龟龄集; 勃起功能障碍; 疗效 　　 　　Clinical observation of Guilingji capsule in the treatment oferectile dysfunction 　　GUO Jun1, ZHANG Chunying2, WANG Rui3 　　1 Department of Andrology in Xiyuan Hospital of China Academy of TraditionalChinese Medicine, Beijing 100091, China 　　2 Department ofUrologyin the Second Affiliated Hospital of Harbin MedicalUniversity, Heilongjiang 150086, China 　　3 Department of Urology in the First Affiliated Hospital of Zhengzhou University , Henan, 450052,China 　　【Abstract】 Objectives: To observe the efficacy of Guilingji capsule in the treatment oferectile dysfunction. Methods: A multi-center, placebo-controlled clinical trial was conducted .A total of 180 patients with erectile dysfunction were randomly divided into two groups: the trial group were treated with Guilingji capsule and the control group were givenplacebo for 4 weeks, The efficacy of patients was evaluated mainly by IIEF-5 and secondarily by concomitant symptoms. Results: 164 patients finished the clinical trial. There are 88 patients in the trial group,36 cases were remarkably effective, 24 cases were effective, 28 cases were ineffective and the total effective rate was 68.2%, There are 86 patients in the control group, 20 cases were remarkably effective, 13 cases were effective, 53 cases were ineffective, and the total effective rate was 38.4%. there are significant differences in statistics between the two groups(P0.01). IIEF-5 score of the trial group were 12.6±2.3 before treatment and 21.8±2