探讨心肌梗死合并糖尿病患者心室重构与血浆内分泌激素水平变化特点.docVIP

探讨心肌梗死合并糖尿病患者心室重构与血浆内分泌激素水平变化特点 　　[摘要] 目的 对心肌梗死合并糖尿病患者采用神经内分泌激素治疗，对患者的心室重构和血浆内分泌激素水平变化进行分析研究，归纳其特点。方法 选择2013年2月―2016年7月在该院接受治疗的76例患者作为研究对象，共36例心肌梗死患者未出现糖尿病症状，将其作为对照组，另外40例患者为心肌梗死合并糖尿病患者，将其作为观察组。对两组患者采取相同的神经内分泌激素治疗，分别对治疗后两组患者的心室重构情况和血浆内分泌激素水平变化进行记录和比较。结果 经过治疗后，两组患者的血浆内分泌激素水平变化差异有统计学意义（P0.05），两组患者的心室重构情况也有明显的区别，观察组患者的左心室收缩末期容积、左心室收缩期末内经和左心室射血分数与对照组比较差异有统计学意义（P0.05）。 结论 心肌梗死合并糖尿病患者进行治疗采用与无糖尿病患者相同的治疗方法时，患者血浆内分泌激素水平的降低情况较差，在患者心室重构方面也存在一定的不良反应，但是仍然有助于改善患者的心功能。 　　[关键词] 心肌梗死；糖尿病；心室重构；血浆内分泌激素水平 　　[中图分类号] R59 [文献标识码] A [文章编号] 1672-4062（2017）05（b）-0013-02 　　[Abstracts] Objective This paper tries to investigate the changes of ventricular remodeling and plasma endocrine hormone levels in patients with myocardial infarction and diabetes mellitus， and to summarize the characteristics of these changes. Methods 76 cases from February 2013 to July 2016 in this hospital were selected as the research objects， regarding 36 patients with myocardial infarction without diabetes symptoms as the control group， another 40 patients with acute myocardial infarction and diabetes mellitus were regarded as the observation group. Two groups of patients were treated with the same neuroendocrine hormone therapy. The changes of ventricular remodeling and plasma endocrine hormone levels in the two groups were recorded and compared. Results After treatment， significant differences occurred in plasma endocrine hormone level in the patients of the two groups（P0.05）， ventricular remodeling in the patients of the two groups also have obvious difference， left ventricular end systolic volume， left ventricular end systolic diameter and left ventricular ejection fraction of the observation group was significantly different from the control group（P0.05）. Conclusion When the same therapy was applied into the patients with acute myocardial infarction complicated with diabetes and without diabetes， the plasma endocrine hormone level of patients receive poor reduction， what’s more， some adverse reactions in pat