北京市西城区20002008年初三学生HBsAg与ALT异常情况分析.docVIP

北京市西城初三学生HBsAg与ALT异常情况分析 　　【摘要】 目的 了解北京市西城区2000-2008年初三学生HBsAg阳性和ALT异常情况,为开展乙肝防治工作提供参考。方法 整群抽取西城区2000-2008年初三学生84 905名,对HBsAg和ALT进行检测。结果 2000-2008年北京市西城区初三学生HBsAg阳性率为0.81%,低于全国平均水平,各年龄组男、女生阳性率差异多无统计学意义,且HBsAg阳性率呈逐渐下降趋势。ALT异常检出率为0.61%,各年龄组男生多高于女生,差异均有统计学意义。结论 西城区初三年级学生HBsAg阳性率和ALT异常率均较低。该区乙肝疫苗预防接种效果较好。 　　【关键词】 肝炎表面抗原,乙型;转氨酶类;患病率;学生 　　【中图分类号】 R 179 G 478.2 R 512.6+2 【文献标识码】 A 【文章编号】 1000-9817(2009)09-0793-02 　　 　　Analysis of Condition of Students in Grade Three with HBsAg and ALT Abnormality in 2000-2008 in Xicheng District in Beijing/ZHANG Ya-juan. School Health Care Institute of Xicheng District in Beijing, Beijing (100037), China 　　【Abstract】 Objective To analyze the condition of students in grade three with positive hepatitis B surface antigen (HBsAg) and alanine aminotransferase (ALT) abnormality of 2000-2008 in Xicheng District of Beijing, and to provide bases for the treatment and prevention of hepatitis.Methods By cluster sampling method, 84 905 grade three students in junior middle schools were chosen to test HBsAg and ALT. Results The incidence of positive HBsAg was 0.81% in students in grade three of 2000-2008 in Xicheng district of Beijing, the positive incidence was less than the national average level-incidence, and there was no significant difference between males and females positive incidence. The incidence of positive HBsAg showed gradual downtrend. The total detection rate of ALT abnormality was 0.61%, there were significant differences between males and females, which indicated that males detection rate was more than females. Conclusion The positive rates of HBsAg and ALT abnormality are lower in grade three junior middle school students in Xicheng district. The Hepatitis B vaccination effect is better in this district. 　　【Key words】 Hepatitis B surface antigens;Transaminases;Prevalence;Students 　　 　　我国属乙型肝炎(乙肝)病毒的高流行区,至少有7亿人已感染过乙型肝炎病毒(HBV),约有1.3亿人携带HBsAg。为控制乙型肝炎的流行,1991年世界卫生组织(WHO)制定了乙型肝炎全球免疫计划,并确定了2010年前全球消灭乙型肝炎的战略目标,其中关键的措施就是