高血压性脑出血早期强化降血压近期预后的临床研究.docVIP

高血压性脑出血早期强化降血压近期预后的临床研究 　　[摘要] 目的 探讨早期强化降血压对高血压性脑出血的近期预后效果情况。 方法 将90例于2011年6月～2013年2月期间入住连州市人民医院治疗急性脑出血的患者随机分为积极降压组和指南降压组，患者入院即开始监测血压。记录入院时患者神经功能缺损程度、日常生活能力、Glasgow 昏迷评分、治疗前后两组患者症状改善以及血肿情况，观察两组患者发病2、14以及30d后临床转归。对患者神经缺损情况和临床疗效进行判定比较。 结果 积极降压组治疗14d后NHISS评分、30d后NHISS评分、总显效率、治疗后14d BI评分及30d BI评分情况分别为：8.5±9.6、5.8±7.6、82.22%、43.56±31.45、60.00±33.45，指南降压组上述数据依次为分别为：10.1±11.7、7.1±10.4、53.33%、40.45±29.75、49.35±29.50，积极降压组各项数据均显著优于指南降压组（P0.05）。 结论 高血压性脑出血早期积极控制血压具有脑保护作用，减少血肿的扩大及病理损伤，且能够促进神经功能恢复，降低致残率、死亡率。 　　[关键词] 高血压性；脑出血；强化降压 　　[中图分类号] R544.1 [文献标识码] A [文章编号] 2095-0616（2014）04-11-04 　　A clinical study on the effects of early intensive blood pressure reduction on short-term prognosis of hypertensive intracerebral hemorrhage 　　LV Meiguang ZHANG Xiaowen SONG Haifeng LI Shujian ZHOU Zhiming 　　Lianzhou Peoples Hospital in Guangdong Province，Lianzhou 513400，China 　　[Abstract] Objective To study and explore the effects of early intensive blood pressure reduction on short-term prognosis of hypertensive intracerebral hemorrhage. Methods 90 patients with acute intracerebral hemorrhage who were admitted to the Guangdong Lianzhou Peoples Hospital from June 2011 to February 2013 were selected and randomly and evenly assigned into a group of active blood pressure reduction and a group of guideline blood pressure reduction.Patients blood pressure had been monitored since admission. Patients degrees of neurologic impairment，activities of daily living and Glasgow coma scores on admission were recorded. Conditions of symptoms alleviation and hematomas were also recorded before and after the treatment.Clinical prognoses in 2，14 and 30 days after the onset in the two groups were observed.Patients degrees of neurologic impairment and clinical effects were then evaluated and compared. Results NHISS scores in 14 days and 30 days after the treatment，total effective rate， BI scores in 14 days and 30 days after the treatment were 8.5±9.6， 5.8±7.6，82.22%，43.56±31.45， 60.00±33.45 respectively