56688例乙型肝炎病毒五项指标定量检测的的结果分析.docVIP

56688例乙型肝炎病毒五项指标定量检测的的结果分析 　　[摘要] 目的 了解南阳地区就医人群乙型肝炎病毒五项指标阳性率的特点及临床意义。 方法 收集2013年1月1日～2014年12月31日在我院住院或门诊就医人群检查乙型肝炎病毒五项指标定量检测的结果，观察不同年龄组男女间各项指标的阳性率是否存在差异。 结果 HBsAg、抗-HBs、HBeAg、抗-HBe、抗-HBc阳性率分别为4.38%、57.12%、0.73%、7.44%和7.61%。除抗-HBe男女各年龄组间差异无统计学意义外，其他四项指标在不同年龄组差异有统计学意义。不同年龄组男女乙肝五项指标阳性构成比差异均有统计学意义（P0.01）。 结论 本地区就诊人群乙型肝炎病毒感染率较低，且存在年龄、性别间差异。20岁以下年龄组感染率更低，抵抗力更强。男性感染率明显高于女性。这种结果与乙肝疫苗接种，女性在此阶段对乙肝病毒的抵抗力和自我恢复能力较男性强有关。 　　[关键词] 乙型肝炎病毒；乙肝五项指标；定量检测；阳性率 　　[中图分类号] R446.6 [文献标识码] B [文章编号] 1673-9701（2016）07-0066-03 　　[Abstract] Objective To understand the positive rate of hepatitis B virus five indicators in populations who seek for doctors in Nanyang area and the clinical significance. Methods The results of quantitative detection of hepatitis B virus five indicators of inpatients and outpatients from January 1st， 2013 to December 31st， 2014 of our hospital were collected and the differences of positive rate of each indicator between different ages and gender were observed. Results The positive rate of HBsAg， anti-HBs， HBeAg， anti-HBe and anti-HBc were 4.38%， 57.12%， 0.73%， 7.44% and 7.61% respectively. The difference of anti-HBe in male and female between each age group had no statistical significance and the other four indicators all had statistical significance. The positive ratio of hepatitis B five indicators in male and female between different age groups had statistical significance （P0.01）. Conclusion Population who seek for doctors in our area has relatively low infectious rate of hepatitis B virus and there are statistical significances between different ages and gender. The group with age under 20 years old has lower infectious rate and better immunity. Infectious rate in male is significantly lower than that of female. This result is associated with the strong immunity and self-recovery ability of female in the hepatitis B vaccination. 　　[Key words] Hepatitis B virus； Hepatitis B five indicators； Quantitative detection； Positive rate 　　乙型肝炎是由乙型肝炎病毒（hepatitis B viru