蓝细菌乙醇光合细胞工厂发展与展望.PDFVIP

生 物 工 程 学 报 齐允晶 等/蓝细菌乙醇光合细胞工厂的发展与展望 891 Chinese Journal of Biotechnology /cjbcn June 25, 2017, 33(6): 891−909 DOI: 10.13345/j.cjb.160457 ©2017 Chin J Biotech, All rights reserved ·综 述· 1,2 1 2 2 2 齐允晶 ，王家林 ，栾国栋 ，谈晓明 ，吕雪峰 1 266042 2 266101 , , , . . , 2017, 33(6): 891–909. Qi YJ, Wang JL, Luan GD, et al. Cyanobacteria cell factories for ethanol photosynthetic production: development and prospect. Chin J Biotech, 2017, 33(6): 891–909. 摘 要: 生物乙醇是极具应用潜力和代表性的生物能源产品之一。以蓝细菌为光合平台，利用二氧 化碳和太阳能直接进行乙醇合成可以同时起到降低二氧化碳排放和提供可再生能源的效果，具有重 要的研究与应用价值。本文回顾了蓝细菌乙醇光合细胞工厂相关技术的发展历程和现状，从途径优 化、底盘选择和代谢工程策略等层面对其最新进展和所遇到的问题进行了总结介绍，并对该技术未 来发展方向进行了展望。 : 蓝细菌，生物乙醇，代谢工程，细胞工厂，乙醇耐受性 Cyanobacteria cell factories for ethanol photosynthetic production: development and prospect 1,2 1 2 2 2 Yunjing Qi , Jialin Wang , Guodong Luan , Xiaoming Tan , and Xuefeng Lü 1 College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, Shandong, China 2 Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, Shandong, China Abstract: Bioethanol is one of the most promising and representative biofuel products. Photosynthetic production of ethanol using CO2 and solar energy based on cyanobacteria is of great significance for research and application, due to the potential to reduce CO2 emission and to provide renewable energy simultaneously. Here we review the history and updated development Received: November 24, 2016; Accepted: January 24, 2017 Sup