第三节农药残留资料讲解.ppt

How to solve it? 解决途径： toxicology 毒理学 毒理学动物实验 Target: different toxicotogical endpoin 研究目标：各种不同毒性程度 Object: the entire animal, microorganisms, or tissue and cell cultures 研究对象：动物、微生物或组织及细胞 Result: extrapolation of animal data to humans 研究结果处理：将在动物体内产生的效应外推到人体当中 Principles of extrapolation 外推的依据 assumed that, in general, the mechanisms of action observed in animals can also be expected to be present in humans. 假定：动物体内的作用机制也可能存在于在人体内 physiological and biochemical similarities between the species are to be expected at least among mammals 物种系统发育具有连续性（包括人体），至少哺乳动物在生理和生化上具有相似性