化石利胆中药对ERP取石术后胆石症患者胆汁成石趋势的影响.docVIP

化石利胆中药对ERCP取石术后胆石症患者胆汁成石趋势的影响 刘杨1赵金满3（通讯 ）林一帆1麻树人2杨卓2巩阳1高文艳 1 （1沈阳军区总医院屮医科110000） （2沈阳军区总医院内镜屮心110000） （3屮国医科人学附属第一医院消化科110000） 】A的：研宂化石利胆屮药对逆行胰胆管造影术（ERCP）取石后的胆 石症患者胆汁成石趋势的影响。方法将144例行ERCP、EST、网篮取石术、ENBD 术的胆石症患者随机分成化石利胆屮药组、熊去氧胆酸（UDCA）组及对照组， 测定术后第1天、第7天、第14天胆汁总胆红素fTB）、直接胆红素（DB）、胆固醇 （CH、磷脂（PHL和总胆盐（TBS）含量，并计算出致石指数（L.I.）、间接胆红素百分比 （UCB%）和胆汁成石趋势综合值（z值），同时进行随访，随访时间3?12个月，平 均6个月；患者每3个月或出现腹痛症状时复查腹部B超、CT、MRCP检查。结 果术后第1天，3组间的L.l.、UCB%、Z值的差异均无统计学意义（P〉0.05）, 丑Z值〉临界值（44.7）。UDCA组和对照组术后第7天与第14天的L.l.、UCB%、Z 值的差异均无统计学意义（P〉0.05,与术后第1天相比，化石利胆屮药组第7天 UCB%降低（PC0.05）;术后第14天，化石利胆中药组的L.I.UCB%、和z值均明显 下降（P0.05, 2值临界值；随访1年后，UDCA组和对照组胆石的复发率无 统计学意义（P〉0.05,化石利胆中药组胆石的复发率明显丁降（P0.05）。结论 化石利胆屮药能调节胆汁成分，从而化石、抑制胆石形成，降低胆石的复发。 关键词】胆石症化石利胆中药胆汁成石 】R243 】A 】1672-5085 （2014） 12-0078-02 Effect of Huashilidan Decoction on the lithogenic tendency in Choledocholithiasis After ERCP Liu Yang 1 Zhao Jinman △ Lin Yifan 1 Ma Shuren 2 Yang Zhuo2 Gong Yang IGao Wenyan 1 (Department of Traditional Chinese Medicine and Gastroenterology,Hospital of Shenyang Military District, The First Affiliated Hospital of China Medical University Department of Gastroenterology, Shenyang 110840) Abstract】 Objective To study the influence of Huashilidan Decoction on the lithogenic tendency in Choledocholithiasis After ERCP. Methods 144 patients with ERCP, EST, ENBD, basket lithotomy surgery cholelithiasis patients were randomly divided into fossil cholagogue herbs group, ursodeoxycholic acid (UDCA) group and control group were determined after first days, seventh days, fourteenth days, bilirubin (TB), direct bilirubin (DB), cholesterol (CH), phospholipid (PHL) and total bile salt (TBS) content, and calculate the lithogenic index (L.L), indirect bilirubin (UCB%) and the percentage of the lithogenic tendency of comprehensive value (Z value), and were followed up.the follow-up time ranged from 3 to 12 months, average 6 months; patients every 3 months or abdominal pain symptoms were abdominal B ultrasound, CT, MRCP examination. Resul