高危型宫颈上皮内瘤变行宫颈锥切术51例治疗价值的探讨.docVIP

高危型宫颈上皮内瘤变行宫颈锥切术51例治疗价值的探讨 　　摘要： ［目的］ 探讨高危型宫颈上皮内瘤变（CIN II级、CIN III级）行宫颈锥切术治疗的临床价值。 ［方法］ 回顾性分析2006年1月1日―2008年8月30日，本院51例因宫颈多点活检诊断为宫颈CIN II级、CIN III级行高频电刀宫颈锥切治疗术患者，对比其一般资料、宫颈多点活检及锥切病理报告。 ［结果］ 高危型患者一般无临床症状(74.50%)，平均年龄38.47岁，锥切术后病理与宫颈活检病理结果相符35例(68.63%)，降级13例(25.49%)，病变升级3例(5.88%)，发现浸润癌1例。48例（94.12%）患者宫颈切缘均阴性，3例（5.88%）患者切缘阳性，术前21例HPV感染患者中有18例转阴。 ［结论］ 随着宫颈上皮内瘤变的患者年轻化，只要正确掌握锥切方法，能有效治疗高危型CIN患者，并能保留女性宫颈内分泌功能、正常性生活生育功能。宫颈锥切术是一种能准确验证宫颈病变并能较好诊断、治疗高危型CIN的方法，且能降低宫颈局部HPV感染，减少持续感染机会。门诊对宫颈糜烂患者进行筛查，锥切术后随访十分必要。? 　　 　　关键词： 高危型； 宫颈上皮内瘤变; 宫颈锥切术; 诊断; 治疗中图分类号：R 713.4文献标志码： B??? 　　 　　Exploration on the clinical value of conization of cervix in 51 cases of high risk type cervical intraepithelial neoplasiaCHEN Jun-qing, LI Hua-qing (Zhejiang Dongyang Peoples Hospital,Dongyang322100, Chian)? Abstract: ［Objective］ To explore the clinical value of conization of cervix in patients of high risk type CIN II、CIN III treated with cervical intraepithelial neoplasia. ［Methods］ Patients who received cervix biopsy and conization were retrospectively analyzed. Among them 51 patients were of high risk CIN and had received conization of cervix in our hospital from January 1st, 2006 to August 30,2008 were recorded. ［Results］The patients of high risk usually had no clinical symptoms. The mean age in this study was 38.47 years.Of the 51 patients, 35 patients (68.63%) had the same pathological diagnosis between cervix biopsy and conization .The pathologic diagnosis of 13 patients (25.49%) were degraded and 3 patientes (5.88%) were upgraded. 0ne invasive cancer was found. 48 patients (94.12%) cervix cutting edge were negative, others were positive. 21 patients infected by HPV turned negative after conization. ［Conclusion］ Correct conization method could cure the high risk CIN. While patients [JP2]tend to become younger and youngerthey could also retain their normal endocrine, sexual life and breeding function. [JP]Conization of cervix is a nonalternative method in diagnosis and treatment ofhigh risk mode