肝脏疾病的实验室检查教学教案.pptVIP

肝脏疾病的实验室检查;Carbohydrate metabolism: Synthesis and storage of glycogen Glycogenolysis and gluconeogenesis Protein metabolism: Synthesis and degradation of proteins ( not immunoglobulins) Amino acid metabolism and urea formation Lipid metabolism: Synthesis of lipoproteins, phospholipids, cholesterol Fatty acid metabolism Bile acid synthesis;Excretion and detoxification: Bilirubin and bile acid excretion Drug detoxification and excretion Steroid hormone inactivation and excretion Miscellaneous: Iron storage Vitamin A, D, E, B12 storage and metabolism;;;;;;;;肝脏病常用的实验室检查目的:;;;胆红素的代谢过程;;;;肝细胞性黄疸时的胆红素代谢;梗阻性黄疸时的胆红素代谢;Laboratory findings in different types jaundices;;Pre-hepatic：liver diseases not present;Case example An 11-year-old boy was jaundiced and generally unwell. his urine, which become dark the day before the onset of jaundice, was positive for bilirubin.;;;;Laboratory findings in different types jaundices;; 血清酶及同功酶检查 肝细胞内酶的定位 ; 血清酶及同功酶检查 肝脏酶的器官定位;Alkaline phosphatase (ALP);;;;;Case example A 26-year-old woman with jaundice, and a dark urine.;Case example A 61-year-old woman with advanced carcinoma of the breast, and radiological evidence of metastatic liver disease.;Case example A 51-year-old woman presenting with deep jaundice, biliary colic and a history of cholelithiasis.;;;Case example A 78-year-old woman with advanced carcinoma that has metastasized to the liver.;Case example Acute infectious hepatitis in a 25-year-old man.;Case example The following results were obtained from three male heavy drinkers aged in their early thirties.; ;Determination of serum enzymes and isoenzymes relative activity of ALT and AST in human tissue;血清氨基转移酶及同功酶检查; ;Case example Anicteric hepatitis A 15-year-old girl complaining of an influenza-like illness. She attended a boarding school where an outbreak of hepatitis had recently occurred. There was no bilirubin in her urine.;Case example Cholestatic acute hepatitis A 35-year-old male, recently returne