我院社区获得性肺炎住院患者抗菌药物使用情况剖析.docVIP

我院社区获得性肺炎住院患者抗菌药物使用情况剖析 　　[摘要] 目的 了解上海交通大学医学院附属第九人民医院（以下称“我院”）社区获得性肺炎住院患者抗菌药物的使用情况。 方法 利用医院信息系统（HIS）抽取我院呼吸内科2016年1～12月诊断为“社区获得性肺炎”的病历。根据《抗菌药物临床应用指导原则》（2015版）对抗菌药物的使用情况进行评价。 结果 经统计，我院收治的91例社区获得性肺炎患者以≥65岁的老年人居多，大多合并基础疾病。抗菌药物使用率为100%，共使用抗菌药物6类13个品种，以喹诺酮类（占80.22%）和β-内酰胺类/β-内酰胺酶抑制剂类（占53.84%）为主。用药方式以两药联合用药为主（73例），主要为β-内酰胺类/β-内酰胺酶抑制剂联合喹诺酮类药。给药方式以静脉滴注给药为主，辅以口服用药。用药期间未有患者发生药物不良反应。 结论 2016年我院社区获得性肺炎患者的抗菌药物使用率高，经验性抗感染治疗以喹诺酮类和β-内酰胺类/β-内酰胺酶抑制剂类单用或联用为主，基本符合《中国成人社区获得性肺炎诊断和治疗指南》中的推荐用药。 　　[关键词] 社区获得性肺炎；抗菌药物；合理用药 　　[中图分类号] R969.3 [文献标识码] A [文章编号] 1673-7210（2017）10（b）-0132-05 　　Analysis of the utilization of antibacterial drugs in patients with community-acquired pneumonia in our hospital 　　ZHU Hui YUAN Yongfang JIN Jian 　　Department of Pharmacy， Shanghai Ninth People′s Hospital， Shanghai JiaoTong University School of Medicine， Shanghai 200011， China 　　[Abstract] Objective To investigate the utilization of antibacterial drugs in patients with community-acquired pneumonia in Shanghai Ninth People′s Hospital， Shanghai JiaoTong University School of Medicine （“our hospital” for short）. Methods The medical records diagnosed with community-acquired pneumonia in Respiratory Medicine Department of our hospital were extracted by HIS from Januaty to December 2016. The utilization of antibacterial drugs was evaluated by Principle for Clinical Application of Antibacterial Drugs （2015）. Results The majority of patients were over 65 years and most of them complicated with basic diseases. The rate of using the antibacterial drugs was 100%， concerning 13 varieties of 6 major categories. The main drugs were quinolones （80.22%） and β-lactam/β-Lactamase inhibitors （53.84%）. The most common way of drug approach was the combination of quinolones and β-lactam/β-lactamase inhibitors with intravenous drip， followed by oral administration. No ADRs happened in patients. Conclusion The rate of antibacterial drugs usage is high in community-acquired pneumonia patients of our hospital. The empirical antib