阿奇霉素口腔崩解片制备工艺与其质量标准-研究.pdf

中文摘要 质、含量均在标准范围内，本品稳定性较好。 结论：本制剂质量稳定可控，使用方便，有利于扩大本 品在临床的应用范围。 关键词：鉴别；溶出度：有关物质；含量测定；稳定性 荚文摘要 one Part Studiesonthe of Technology tablets Azithromycinorallydisintegrating ABSTRACT is a fifteen—membered Azithromycin heterocyclic whichhas antibacterial for compound， good activity extracellular andintracellular with pathogen．Comparedadopted hasthe characteristic：1． macrolide(erythromycin)，it following Aziisactive themicrobc+hat against isinsensitivetomacrolide antibiotic．And avails Azithromycinagainstpneumonia andinfectionofthe chlamydia，pneumonia mycoplasma causedflora，withwhichtoo respiratoryby farbehindtocatch up shows no tolerance drug for aureus staphylococcusproducing lactamase，moraxella，diplococcus gonorrhoeae．3．Itspreads intissues，butits widely concentrations from prominentlyvary low to asfollows，the of mucous high macrophagelung，the membraneofthebronchial tissue．