瑞替普酶溶栓治疗120例急性心肌梗死疗效剖析.docVIP

瑞替普酶溶栓治疗120例急性心肌梗死疗效剖析 　　[摘要] 目的 研究瑞替普酶溶栓治疗急性心肌梗死的效果。 方法 选取我科2005年3月～2012年12月期间收治的120例急性心肌梗死患者，随机分为对照组与实验组。对照组患者运用尿激酶治疗，实验组患者运用瑞替普酶溶栓治疗，对比两组患者的临床治疗效果。结果 治疗后，对照组的总有效率明显低于实验组，血管再通率低于实验组，血管开通的时间长于实验组（P0.05）。 结论 瑞替普酶溶栓治疗急性心肌梗死具有出血程度低、血管开通率高、血管开通时间短等优点，值得临床推广。 　　[关键词] 瑞替普酶；临床疗效；尿激酶；急性心肌梗死 　　[中图分类号] R542.22 [文献标识码] B [文章编号] 1673-9701（2013）36-0127-02 　　Analysis on efficacy of reteplase thrombolytic therapy for 120 cases of acute myocardial infarction 　　ZHONG Xiaoming 　　The Second Department of Internal Medicine， Peoples Hospital of Yifeng County in Jiangxi Province， Yifeng 336300， China 　　[Abstract] Objective To study the efficacy of reteplase thrombolytic therapy in the treatment of acute myocardial infarction. Methods A total of 120 cases of patients with acute myocardial infarction who admitted to our department from March 2005 to December 2012 were randomly divided into control group and experimental group， the patients of control group were treated with urokinase， while the experimental group were treated with reteplase thrombolytic therapy， the therapeutic effect of the two groups were compared. Results After the treatment， the total effective rate of control group was significantly lower than that of experimental group， recanalization rate was lower than that of the experimental group， and the time of recanalization was longer than that of the experimental group. Conclusion Reteplase thrombolytic therapy have the advantages of lower degree of bleeding， higher recanalization rate， and shorter time of recanalization in the treatment of acute myocardial infarction， so its worthy of clinical promotion. 　　[Key words] Reteplase； Clinical curative effect； Urokinase； Acute myocardial infarction 　　急性心肌梗死（Acute myocardial infarction，AMI）指的是人体的冠状动脉出现堵塞，心肌因为缺血过于严重导致其局部地区坏死的临床病症。因为冠状动脉粥样硬化斑块出现碎裂，导致在冠状动脉血管里面出现急性的血栓，从而致使冠状动脉在急性供血方面出现缺失，最终导致心肌发生缺血与缺氧的状态。该疾病发病具有一定的突发性，其发展速度非常快，并会同时导致心力衰竭、心源性休克等各类症状。所以，如果不能够进行及时的治疗，患者将会有生命危险。现阶段，通过大量临床治疗实践证实，在心肌梗死前期实施对应的措施，能够让病变区域的冠状动脉进行再一次