非甾体抗炎药所致大鼠小肠黏膜损伤及保护作用的机制研究-中医学专业论文.docxVIP

万方数据 万方数据 Abstract Objective Administrating rats with low dosage diclofenac in short-term to induce the small intestinal damage. Observing the small intestine mucosa damage as well as the blood serum NO expression influenced by diclofenac, and observing the preventive effect to NSAIDs induced small intestinal damage by metronidazole and rabeprazole , thus to provide the experimental foundation for prevents and controls this damage. Methods 64 rats were divided into 4 groups(control group, model group, metronidazole group and rabeprazole group), and each group with 16 rats were separ