串联质谱法测定牛奶中氯霉素残留量的不确定度评定-食品安全质量.PDF

7 7 Vol. 7 No. 7 2016 7 Journal of Food Safety and Quality Jul. , 2016 - 李 静, 夏苏捷, 刘晓云, 王 柯, 刘 畅* ( , 201203) 摘 要: 目的 -方法 GB 29688-2013 -, JJF 1059.1-2012 结果 0.1064 ng/g , 0.1064±0.0457 ng/g(k=2)结论 , , - 关键词: -; ; ; Uncertainty evaluation of chloramphenicol in milk by high performance liquid chromatography-tandem mass spectrometry * LI Jing, XIA Su-Jie, LIU Xiao-Yun, WANG Ke, LIU Chang (Shanghai Institute for Food and Drug Control, Shanghai 201203, China) ABSTRACT: Objective To evaluate the uncertainty in determination of chloramphenicol in milk by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Methods According to GB 29688-2013 The determination of chloramphenicol in milk by high performance liquid chromatography-tandem mass spectrometry, the uncertainty model was established. According to JJF 1059-1999 Evaluation and expression of uncertainty in measurement, the main sources of the uncertainty resulted from the determination process were discussed and calculated. Results The major uncertainty sources were curve calibration and the repeatability test. When the chloramphenicol content in dairy products was 0.1064 ng/g, the uncert