β-榄香烯的分析检测方法及制备技术研究进展-中国现代应用药学.PDF

β-榄香烯的分析检测方法及制备技术研究进展 黄汉昌a,b a,b c* ，姜瑞瑞 ，张明贤 (北京联合大学，a.生物活性物质与功能食品北京市重点实验室，b.应用文理学院，c.生物化工程学院， 北京 100191) 摘要：目的 介绍β-榄香烯的分析检测方法及制备技术研究进展。方法 本文对榄香烯的双键异构及β-榄香烯的光学异 构体分子结构、分析检测方法及制备技术进行了综述；进一步评述从天然植物中提取及分离 β-榄香烯的方法及技术的优 缺点。结果与结论 气相或液相色谱结合核磁、质谱等光谱技术能较好地检测β-榄香烯成分及含量；众多植物挥发油富 含β-榄香烯，采用真空精馏及柱层析联用技术能获得高纯度的β-榄香烯。 关键词：β-榄香烯；提取；分离；分析 中图分类号：R284.2; R917 文献标志码：A 文章编号：1007-7693(2011)02-0116-06 The Progress on Analytical Methods and Isolated Techniques on the Development of β-Elemene HUANG Hanchanga,b, JIANG Ruiruia,b, ZHANG Mingxianc*(Beijing Union University, a.Beijing Key Laboratory of Bioactive Substances and Functional Foods, b.College of Arts and Science, c.College of Biochemical Engineering, Beijing 100191, China) ABSTRACT: OBJECTIVE To review the progress of β-elemene on the analytical methods and isolated techniques. METHODS This article provides an overview about the structures of elemene’s cis-trans isomers and optical isomers of β-elemene, the analytical methods and isolated techniques of β-elemene, and further comment of advantages and disadvantages on the extraction and isolation of β-elemene from natural products. RESULTS and CONCLUSION β-elemene will be well detected by gas or liquid chromatography plus spectrum techniques, like nuclear magnetic resonance (NMR) and mass spectrum (MS). β-elemene is contained on a host of essential oils and will be well isolated by the combined techniques of vacuum distillation and column chromatography. KEY WORDS: β-elemene; extraction; separation; analysis 基金项目：北京市教育委员会科技计划项目(KM201011417002) * 作者简介：黄汉昌，男，硕士，助理研究员