高分辨力超声测量动脉粥样硬化斑块纤维帽厚度的研究-影像医学与核医学专业论文.docxVIP

硕士学位论文 硕士学位论文 中文摘要 低回生区域所包绕(管腔内血液组织和脂质核心)，纤维帽变薄者其斑 块的稳定性亦随之降低，更容易破裂，从而发生心脑血管意外。此外， 斑块内脂质核心／斑块的比值也可作为检测斑块稳定性的指标，该比值 40％时，斑块破裂的风险增加。颈动脉超声检查作为一种无创性检查 方法，能很好的监测动脉粥样硬化病人斑块的稳定性，对其破裂风险和 临床急性事件的预测有着重要意义。 关键词高分辨力超声，纤维帽，颈动脉粥样硬化斑块，不稳定性 II 硕士学位论文 硕士学位论文 英文摘要 ABSTRACT objective To describe the imaging of atherosclerotic plaque fibrous cap in carotid by the color Doppler ultrasonographic and to study the relationships between the fibrous cap thickness(FCT)and the stability of plaques，and to investigate the values of carotid ultrasonagraphy for evaluating the stability of carotid atherosclerotic plaque． Methods Forty—nine pereons，25 ischemic cerebrovascular disease patients，24 patients who have no ischemic cerebrovascular disease．were examined by the the color Doppler ultrasonographic unit of Acuson Sequoia 5 12．The examining parts of these Patients include the double com／Ilon carotid artery,the carotid arterial bifurcation and the intemal carotid artery．We observation the size and characteristic of plaques，the fibrous cap thickness(FCT)，the carotid ttmica intima．media thickness OMT)，the normal lumens volume of carotid．the stenosis lumens volume of carotid．the volume of plaque，the lipid core’S volume in plaque，the Systole Maximum velocity (Vmax)and Diastole Minimus velocity(Vminl were measured．The resistant index(Rj)，Systole Maximum velocity／Diastole Minimus velocity(S／D)，the mean thickness(mean FCT】、the max thickness fmax FCT)and the min thickness(min FCT)of the fibrous caDS、the stenosis degree of carotid and the ratio of lipid core and plaque calculated by the apparatus automatically． Results Firstly,the comparison of the symptomatic plaque group with the asymptomatic plaque group shows that the 1Tlax FCT、the min FCT、the mean FCT increased significantly QO．01)，while the ratio oflipid core and plaque increased significantly①O．05)；To compared with the asymptomatic plaque group，the Systole Maximum velocity(Vmax)and Diastole Minimus velocity(Vmin)of the normal carotid and stenos