踝臂指数与冠心病及其高危因素的相关性研究-心血管内科学专业论文.docxVIP

硕士学位论文 硕士学位论文 中文摘要 摘 要 目的：通过测量冠心病和／或有三个或以上心血管疾病危险因素 的患者的踝臂指数，分析与其异常相关的心血管危险因素之间的关 系。 方法：选2007年9月至2008年2月在我院心血管内科住院的 190例有冠心病和／或有三个或以上心血管疾病危险因素的患者为研 究对象，同时测量其上下肢血压，计算踝臂指数(ABI)，ABI_0．9定 义为异常。分析研究对象ABI异常的发生情况及与其相关的其他心 血管危险因素。 结果：1、ABI值在ABI异常组和ABI正常组中分别为0．82±0．08 和1．13±O．10，差异有统计学意义。 2、190例患者中共检测出ABI异常者57例(30％)，其中男性 37例(31．63％)，女性20例(27．40％)。 3、与ABI正常组比较，ABI异常患者的年龄更大，冠心病、糖 尿病、高血压、血脂异常者所占比例亦大，而性别、体质指数及吸烟 者的比例无差别。 4、Logistic回归分析显示冠心病、糖尿病、高血压及血脂异常与 ABI异常有关，而年龄、性别、体质指数和吸烟与ABI异常无关。 结论：ABI异常的发生率在冠心病及其高危患者中较普通人群 高。ABI异常患者的年龄更大，有更高比例的冠心病，糖尿病，高血 压以及血脂异常患者。在临床工作中应更重视ABI的测量，尤其是在 硕士学位论文 硕士学位论文 中文摘要 老龄和心血管疾病的高危患者中。 关键词：踝臂指数，冠心病，高血压，糖尿病，危险因素 II ABSTRACTObj ABSTRACT Obj ectives：The aims of this study were to investigate the prevalence of abnormal ABI in patients with documented coronary heart disease and／or with 3 or more risk factors of cadiovascular disease and to analyze the relationship between abnormal ABI and the cardiovascular risk factors． Methods：Selecting 1 90 hospitalized patients with coronary heart disease and／or with 3 or more risk factors of cardiovascular disease from department of cardiology from September 2007 to February 2008．ABl was calculated from the ratio of systolic blood pressure of ankle artery to systolic blood pressure of branchial artery．Abnormal ABl was defined as ABI_0．9．Data were analyzed to investigate the prevalence of abnormal ABI in all subj ects and to explore the association of risk factors with abnormal ABI． Results：1．The value of ABl was 0．82±0．08 in the abnormal ABI group and 1．1 3±O．1 0 in the normal ABI group．The difference was significant statistically between these two groups． 2．The prevalence of abnormal ABl was 3 0％in overall，3 1．63％in men and 27．40％in women，respectively． 3．Compared with participants with normal ABI，those with abnormal ABl were significantly older and had higher proportion of comary heart disease，diabetes mellitus，hypertension and lipid disorders． III 硕士学位论文 硕士学位论文 英文摘要 The distribution of gender,body mass index and pr