大学文献研究Uptake of Retrograde Tracers by Intact Optic Nerve Axons A New Way to Label Retinal Ganglion Cells.pdfVIP

RESEARCH ARTICLE Uptake of Retrograde Tracers by Intact Optic Nerve Axons: A New Way to Label Retinal Ganglion Cells Yu-Xiang Liang1,2☯ *, Jian Yang2☯, Ti-Fei Yuan3,4 *, Kwok-Fai So1,2,3,5* 1 State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong, China, 2 Department of Anatomy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China, 3 Department of Ophthalmology, the University of Hong Kong, Hong Kong, China, 4 School of Psychology, Nanjing Normal University, Nanjing, China, 5 GHM Institute of CNS Regeneration, Jinan University, Guangzhou, China ☯ These authors contributed equally to this work. * hrmaskf@hku.hk (K-FS); yxliang@hku.hk (Y-XL); ytf0707@126.com (T-FY) Abstract OPEN ACCESS Retrograde labelling of retinal ganglion cells with optic nerve transection often leads to de- Citation: Liang Y-X, Yang J, Yuan T-F, So K-F (2015) Uptake of Retrograde Tracers by Intact Optic Nerve generation of ganglion cells in prolonged experiments. Here we report that an intact optic Axons: A New Way to Label Retinal Ganglion Cells. nerve could uptake retrograde tracers applied onto the surface of the nerve, leading to high PLoS ONE 10(6): e0128718. doi:1