tnfα拮抗剂使用过中结核的筛查与管理.pptVIP

* * * There are two commercial assays available in the world. The first of these, called the QuantiFERON TB test Gold is available in the United States. The test works like this. First blood is drawn into an heparinized tube. The cells are separated and stimulated with various antigens including positive and negative controls. After incubation, sensitized T cells produce interferon that can be harvested and measured using an ELISA assay. The results are interpreted by a computer program. * * For assessing sensitivity, the study sample had to have microbiologically confirmed active tuberculo