南京工业大学-生物分离工程chapter细胞破碎.pptVIP

The mechanical methods described in Section 4.3 are dominated by homogenization and by ball mill grinding. In both cases, cells are broken by high mechanical shear. Heat generation is a problem and scale-up is obscure: If we find that a method works at a laboratory scale, we often have little idea how it will work at a large scale. As a result, this part of the chapter is more a guide to planning experiments than a synopsis of engineering analysis. 4.3节机械法主要有匀浆法和研磨法。这两种方法中，细胞通过高的机械剪切力被破坏。热量的产生是该法的一个缺点，而且不容易规模放大:如果一种方法可以在实验室规模下操作，我们并不知道这种方法是否在大规模生产中可行。所以，这部分内容仅作为实验的指导，而不是工程分析。 Such cells have