Systematic Reviews and MetaanalysisHome Page 系统综述和Meta分析.pptVIP

Critical Appraisal of:Systematic Review: Bisphosphanates and Osteonecrosis of the Jaw Basil Al-Saigh August 2006 What is Systematic Review? Systematic Review : Based on protocol Involves critical appraisal Synthesis of the data Meta-analysis: Statistical combination of data Systematic vs. Narrative Reviews Why do a Systematic Review? To examine the quality of the evidence To summarize the treatment benefit in a given therapeutic area – provide the best estimate of its direction and magnitude To resolve discordance between trials To investigate reasons for the discordance Formul