IV期肿瘤患者放疗.pptVIP

下载本文档

8
0
约1.66万字
约 47页
2018-12-21 发布于浙江
举报
版权申诉

IV期肿瘤患者放疗.ppt

1、本文档共47页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
8、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

* Radiation Therapy Oncology Group (RTOG 74-02).27 Ninety percent of patients experienced some relief of pain and 54% achieved eventual complete pain relief. The conclusion was that protracted dose-fractionation schedules were more effective than short-course schedules * Radiation Therapy Oncology Group (RTOG 74-02).27 Ninety percent of patients experienced some relief of pain and 54% achieved eventual complete pain relief. The conclusion was that protracted dose-fractionation schedules were more effective than short-course schedules * The fields for upper HBI cover the thorax and abdomen from the neck to the top of the iliac crests. For midbody HBI, the fields include the abdomen and pelvis from the diaphragm to the ischial tuberosities, and for lower HBI treatment, the field borders are from the top of the pelvis to the inferior portion of the femurs. * Several conclusions are clear from these studies: a. Single dose treatments of 8 Gy provide similar pain relief to longer treatment regimens (30 Gy in 10 fractions or 20 to 24 Gy in five to eight treatments). b. The retreatment rates are higher after short course treatment, by a factor of 2 to 3. c. Response rates are lower when scored by the patient instead of by the treating physician. d. Response rates are better when the initial pain scores are lower, that is, when the patients are treated for moderate pain rather than severe pain. e. There is no consistent dose response relationship for palliation of bone metastases. 多次分割的随机临床研究比较作者病例数剂量(Gy/Fx) 完全缓解(%) 总缓解(%) 病理骨折(%) Tong et al.,1982 美国（单发病灶） 266(146) 20/5 40/15 53 61 82 85 4 18 Tong et al.,1982 美国（多发病灶） 750（613） 15/5 .20/5 25/5 30/10 49 56 49 57 87 85 83 78 5 7 9 8 Hirokawa et al., 1989 日本 128（128） 25/5 30/10 NA 75 75 NA Rasmusson et al., 1995 丹麦 217（127） 15/3 30/10 NA 69 66 NA Niewald et al, 1996 德国 100（100） 20/5 30/15 33 31 77 86 8 13 单次与多次分割的随机临床研究作者病例数剂量(Gy/Fx) 中位生存完全缓解总缓解复治率病理骨折 Kaasa et al.,2006 376 8/1 vs. 30/10 9.6 7.1 NA 无差异