pharm开acology1.pptVIP

Pharmacology药理学Chapter 1Introduction What is pharmacology? What is pharmacology? What is pharmacology? Highlights of theHistory of Pharmacology More Recent Research Developments Gene therapy Chapter 2 PharmacokineticsPart 1Absorption 吸收Distribution 分布Elimination 消除(including of )of drugs 1. Absorption 吸收 First-pass elimination (首过消除) 2. Distribution 分布 The Blood-Brain Barrier Binding to Proteins 蛋白质 3.1 Metabolism 代谢 CYP450 Monooxygenase system 细胞色素P450单氧化酶系统 Substrates of human CYPs Some drugs are enzyme-inhibitors (m metabolism), drug interaction!ex, phenobarbital 苯巴比妥 inhibi