基于GIS技术的广东省儿童青少年白血病空间分析-流行病学与卫生统计学专业论文.docxVIP

Study on the Spatial Analysis of childhood leukemia in Guangdong province based on GIS technology Postgraduate: Guan-wen Lin Supervisior: Prof. Jin-xiang Ma Abstract Objective: GIS has been applied to mining spatial information data of childhood leukemia in Guangdong province,and using different spatial weight matrixes to analyze the spatial autocorrelation and the spatial distribution pattern,to analysis the spatial aggregation of incidence and the hot and cold areas,and to explore the association between leukemia incidence and heavy metal in topsoil, to provide evidence for the prevention and control of childhood leukemia. Methods: Login the GPSspg HYPERLINK / website(), query each case coordinates of latitude and longitude online, established the database of childhood leukemia cases geographic coordinate.By using the ArcGis 10.0,all the cases was accurate spatial location in Guangdong Province map and visualization mapping. Based on first-order,second-order, third-order Rook and Queen spatial weight matrix,threshold weight matrix and K-nearest neighbor weight matrix,the spatial autocorrelation was carried out by GeoDa0.9.5-i. Established the incidences database of guangdong province different counties and cities of childhood leukemia,ArcGis 10.0 was applied to analyze the spatial association.Using the GeoDa and ArcGiS to carry out the local autocorrelation analysis and hotspot analysis Results: Four spatial weight matrix analysis of the global Moran s I values were statistically significant. The global Moran s I=0.3424,0.3595,0.4019 and 0.4906(p ＜ 0.05),while in first-order Rook and Queen weight, smallest threshold and K=3.Childhood leukemia cases was aggregated distribution in Guangdong Province. Hot spot analysis illustrated that there was cluster with highter incidence of childhood leukemia in Guangdong province, especially in Jiangmen Zhongshan and Shunde(Z＞1.96), and it is related to the Hg,Cu and Pb level of heavy metal in topsoil （ rs=0.772,P=0.002; rs=0