表面上和纳米孔道内以及乳液中的手性催化-分子催化与原位表征研究组.PDF

29 9 　　　 2008 9 Vol.29 No.9 ChineseJournal of Catalysis September 2008 :0253-9837(2008)09-0789-28 :789～816 韩涤非, 　杨启华, 　李　灿 (中国科学院大连化学物理研究所催化基础国家重点实验室, 辽 大连 116023) :, 、 .、 , , 、、、、、Aldol Diels-Alder ., 95%ee 20 000 h-1 TOF, 90% ee ;, Aldol 99%ee , 5 -1 , TOF 3×10 h ; , , .、、 . :;;;;;;; :O643　　　:A Heterogeneous Chiral Catalysis on Surfaces, in Nanopores and with Chiral Emulsions HAN Difei, YANG Qihua, L I Can ＊ (State Key Laboratory of Catalysis, Dalian I nstitute of Chemical Physics, The Chinese Academy of Sciences, Dalian 116023, L iaonin , China) Abstract: eterogeneouschiral catalysis isone of thepotentialstrategies for thesynthesisof chiralchemicals.To develop high efficient and selective heterogeneous chiral catalysts isof both scientificinterests and application po- tentials.In this review, we present the research progress of heterogeneous chiral catalysis on surfaces, in nanopores, and with emulsions and mainly focuses on the recent progresses on chiral hydrogenation, hydrogen transfer, hydroformylation, epoxidation, hydrolytic kinetics resolution, Aldol reaction, Diels-Alder reaction, enzyme catalytic reaction, etc.made in this laboratory.The chirally modified nanocatalysts can catalyze hydro- -1 genation of α-ketoester with 20 000 h TOF and more than 95%ee;up to 90%ee can be obtained for the hy- droformylation on chirally modified Rh nanocatalysts.Asymmetric Aldol reaction in chiral emulsion gives 99% 5 -1 ee and increased activity.Up to 3×10 h TOF can be achievedfor emulsion hydrogen transfer.The pore ef- fects can