基于ct图像的计算机辅助恶性肝肿瘤分割研究-计算机应用技术专业论文.docxVIP

II II 域，采用球形计分滤波器的方法对较小的肝肿瘤和肝癌转移进行检测，并 采用灰度共生矩阵（Gray Level Co-occurrence Matrix GLCM）生成的纹理 特征量——对比度，以及其他的特征量来删除候补区域的假阳性。 关键词：计算机辅助诊断 CT 图像 二值图像 薄板样条 球形计分滤波器 III III COMPUTER-AIDED LIVER TUMOR SEGMENTATION RESEARCH BASED ON CT IMAGES ABSTRACT Nowadays, Primary liver cancer is a disease with high mortality rate due to the small amount of nerves inside the liver organ. Therefore, a slight liver disease or damage is difficult to be found out by human observers, and the initial cancer in liver has a long incubation period with relative smaller volume, no obvious clinical symptom, and so on. These features make it very difficult for a doctor to undertake visual diagnosis of liver cancer in early stage even with the help of some medical imaging tools such as Computed Tomography (CT), especially to the young residents who usually make missed diagnosis because of less clinical experience. As a result, tumor diagnosed as cancer is always in the middle-late stage, which leads to great difficulty in treatment of the liver cancer and the cure rate is extremely low. Therefore, developing an effective computer-aided diagnosis system to help doctor to diagnosis liver disease is essential and significant in clinical practice. This paper describes a novel method for the malignant liver tumor segmentation in the computer-aided diagnosis system as the following three parts: Registration of soft organs in abdominal CT phased images, including Phase-Only Correlation (POC) rigid registration and Thin-Plate Spline (TPS) PAGE PAGE VI non-rigid registration, showing that 17 landmarks selected in the liver contour with TPS method for non-rigid registration can achieve satisfactory registration result. Aiming at overcoming the disadvantage of the manually selected landmarks, we proposed a novel method of selecting landmarks automatically based on liver binary image. The new detecting landmarks method can find out a number of landmarks to meet the registration requirements, and the experimen