脊髓缺血损伤模型及行为学的实验研究.docVIP

脊髓缺血损伤模型及行为学的实验研究 Experimental research on the model and behavior of spinal ischemia injury Update date: 2011-01-01-18, wang zhengguo of wang zhengguo of the wangs Abstract: objective to make a new model of rabbit spinal ischemia injury, and observe its behavior change? Methods in order to selectively block the lumbar artery, 32 rabbits were randomly divided into the control group, and the blood loss was 30, 60 and 90 min group? Using the Jacobs method to rate the function of the hind limb of the rabbit, the Reuter method graded the function of the sensory motor reflex of the spinal cord. The resuIt was a total of 1 cl, with 30 minutes of ischemia, a mild paralysis of 30 min and 60, 90 min of the total (8/8) complete paraplegia? The trend of Reuter，s variation was in the 90 min group ischemic group ischemic group , 30 min group control group? Conclusion the blood flow of the lumbar artery was 30, 60, 90 min, which can simulate the light, middle and weight of local spinal ischemia reperfusion injury. This model is an ideal model for spinal ischemia injury. Key words: rabbit; Spinal cord injury; Local ischemia; behavior Experimental Study on ischemic injury model of spinal cord and behavior WU Yamin WANG Zhengguo ZHU Peifang, et al. (The Research Institute of Surgery, Daping Hospital, The Third Military Medical University, Chongqing 400042, China) Abstract: ObjectiveTo make a new ischemic injury model of spinal cord and investigate the function changes of behaviors in rabbits? MethodsThe ischemic injury model of spinal cord was created by the selective occlusion of lumbar arteries in 32 rabbits, which were randomly and equally means into four groups, i. e. for the control group, ischemia for 30 minutes, ischemia for 60 minutes and ischemia for 90 minutes? The function of hind extremities was evaluated by the Jacobs method; and the sensory, motor and reflex functions of spinal cord were scored through the Reuter method? Results A mild paralysis was noted in the isc