超声血流向量成像技术评价2型糖尿病患者左心室流体力学变化影像医学与核医学专业论文.docxVIP

左．3- 左 ．3- 万方数据 Assessment Assessment of intra-ventric ula r fluid dyna mic changes of left 一 ventricle using uitraso nlC vector llow ma pplng m patie nts Witn 锣pe 2 dia betes mellitus Abstract：Objective：To evaluate the intra-ventricuhr fluid dynamics of leR ventricle in patients with type 2 diabetes(D2M)mellitus during diastolic period and isovolumetric contraction phase Ovc)，and to explore the clinical value of leR intra-ventricuhr energy loss(EL)assessment of left ventricle ush培 ultrasonic vector flow mapping for quantitatively evaluation of left ventricular diastolic dysfunction and the potential changes of hemodynamic during IVC． Methods：Sixty two patients with D2M were selected randomly as case group and nli啊nine normal adults were employed as control group．Dynamic images of standard two-dimens ional cardiac views with gray-scale and spectral Doppler and apical 3 chambers(AP3c)view with color Doppler flow during three completed cardiac cycles were acquired for the measurement of general parameters of leR ventricle and left atrium,diastolic and systolic function of left ventric le．The AP3c color Doppler flow images were analyzed further using an off-line dedicated workstation to acquire the leR intra-ventricular EL parameters during diastolic phases and IVC，and vortex circulation(Cir)and vortex area and the position of vortex center(vortex-X and vortex-Y)durillg IVC and diastolic phases identified based on the time-rioW curve(T-F curve)of left ventricular inflow tract and the open-close of valve．Diastolic phase and IVC of left ventricle were divided into the isovohmic relaxation phase口1)， early diastolic phase口2)，rapid filling phase?3)，slow filling phase口4)，atria contract period(P5)and isovohmetric contraction phase@6)．The EL parameters of each phase(Pn-EL，n-1巧)and vortex parameters of IVC were recorded simultaneously．The difference of general parameters and vortex parameters in IVC and EL value of each diastolic and IVC phasesⅥ骶 万方数据 compared．The compared．