疏补温肾固肠方治疗腹泻型肠易激综合征的疗效观察.pdf

疏补温肾固肠方治疗腹泻型肠易激综合征的疗效观察 ＊ # 张 琼 ，陈定玉 （重庆市中医院，重庆 400011） 中图分类号 R272.1；R574.62 文献标志码 A 文章编号 1001-0408（2014）35-3338-03 DOI 10.6039/j.issn. 1001-0408.2014.35.24 摘 要 目的：研究疏补温肾固肠方治疗腹泻型肠易激综合征（IBS ）的临床疗效。方法：60例患者随机均分为治疗组和对照组， 治疗组使用疏补温肾固肠方，对照组使用匹维溴铵片联合马来酸曲美布汀胶囊。治疗4周后，根据结肠问卷表、大便性状表 （IBS-DSQ ）、生活质量量表（IBS-QOL ）判定疗效。结果：两组患者治疗前后中医症状积分比较，差异均具有统计学意义（P ＜ 0.05），且治疗组优于对照组（P ＜0.05）；两组患者治疗前后大便性状疗效总有效率，治疗组为76％，对照组为56％，差异具有统计 学意义（P ＜0.05）；两组患者IBS-DSQ 中的排便次数、肛门坠胀时间比较，差异有统计学意义（P ＜0.05），且治疗组优于对照组（P ＜ 0.05）。两组患者IBS-QOL 中情绪状况、精神状况、日常社交、工作影响的积分差值差异具有统计学意义（P ＜0.05）。结论：疏补温 肾固肠方治疗腹泻型IBS 效果良好。 关键词 疏补温肾固肠方；腹泻型；肠易激综合征；临床疗效 Efficacy Observation of Shubu Wenshen Guchang Decoction in the Treatment of Diarrhea-predominant Irri- table Bowel Syndrome ZHANG Qiong ，CHEN Ding-yu（Chongqing Hospital of TCM ，Chongqing 400011，China ） ABSTRACT OBJECTIVE ：To study the clinical efficacy of Shubu wenshen guchang decoction in the treatment of diarrhea pre- dominant irritable bowel syndrome （IBS ）. METHODS ：60 patients were randomly divided into treatment group and control group. Treatment group received Shubu wenshen guchang decoction ，while control group was given Pinaverium bromide tablets and Trime- butine maleate capsules. Therapeutic efficacy was evaluated after 4 cycle of treatment according to colon questionnaire ，IBS-DSQ and IBS-QOL. RESULTS ：The TCM symptom score of 2 groups had statistical significance before and after treatment （P ＜0.05）， and that of treatment group was better than that of control group （P ＜0.05）. Therapeutic efficacy of stool proferty was 76％in treat- ment group and 56％in control group ；there was statistical significance （P ＜0.05）. The defecation times and anal bearing-down time of IBS-DSQ had statistical significance between 2 groups before and after treatment （P ＜0.05），and those of treatment group were better than those of control group （P ＜0