榄香烯碘油抗癌药栓塞乳剂的实验研究.PDFVIP

706 1999 12 15 12 Original Papers 　李　萍 　　: ELE LIP , , : MMC ELE 60% UR , 40% LIP , , , EIE Z KS- 4 MMC , , , , P KBP - N 1 : LM E41 51, 13. 5 h 8 h, , 20100 um , 41, , , 51LMU53 : , LME41 51, LMU 5 3 , The Experiment Study on Anti- cancer Embolism Emulsion of Elemene Lipiodol L i P ing The Th ird Af f iliated H osp ital of N anj ing M ed ical Univ ers ity , N angj ing 211900 ABSTRACTObj ecti e: T investigate the applicability , the phy sical stabilizati n, release rate and size f emulsi n granular in the . : 40% 60% , different rat i n f ELE and emulsifying emb lism agent Methods M MC w as diss lved in LIP r UR then it w as mix ed w ith 40% LIP in the different rati n by means f Tw pumps- Int erval, the separate time f il- water was bserved and rec rded in r m temperature. The separati n f il- w ater, the change and characteristic f emulsi n particles w ere studied by m icr sc pe, s the size f emulsi n part icles in different rati n were measured by the standard ELE nes. The c ntent f MMC was determined w ith - 4 . , ZKS intelligence diss lve in the manner f Jiang Y e The release accumulated percent age was c unted its abs rpti n value w as sur - veyed by ultravi let and linear regressi n was made in distinct c ncentrati n. Finally , its standard curve equati n w as evaluated and re- lease parameter was c unted acc rding t Weber s f rmula in P KBP - Ni pr gram. Result: LME 41 and 51 separated sl w, the 13. 5 8 , 20100 , 41 c mplet e separat i n time w as and h urs respectively t he stable size f granular w as um the rati n f w as the best