呼吸支持新技术的临床应用与评价2八011解立新.pptVIP

* 吸入一氧化氮（iNO） Effect of nitric oxide on renal dysfunction for ALI-A Meta Analysis BMJ . 2007 ; 334 ( 7597 ): 779 Nitric oxide increased the risk of renal dysfunction in one unblinded and three blinded trials that enrolled 72% of patients in all included trials (risk ratio 1.50, 1.11 to 2.02) Despite the lack of evidence that iNO improves important outcomes, it is used as rescue therapy for refractory hypoxemia Clinically significant improvement in oxygenation following initiation of iNO should be demonstrated within the first hour of therapy to justify continued use Dose-ranging studies sugges