舒肝颗粒对大鼠肝星状细胞的凋亡作用.pdf

Effect of Shugan granule on Hepatic Stellate Cell apoptosis Abstract: Objective: Chronic hepatic injury usually leads to the development of Liver fibrosis and the activated HSC seems to play the main role in its pathogenesis. Activation of HSC leads to the overproduction and deposition of the ECM leading to liver fibrosis, the subsequent cirrhosis. Thus, by inhibiting HSC activation, inducing HSC apoptosis, thereby restraining the collagen production, can